Editorial

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Progress toward realizing the promise of decentralized clinical trials

Matthew W. McCarthy, Christopher J. Lindsell, Radha Rajasingham, Thomas G. Stewart, David R. Boulware and Susanna Naggie

Published online by Cambridge University Press:  29 January 2024

Research Article

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“And then I found $5”: Optimizing recruitment efficiency in remote clinical trials

Margaret C. Fahey, Jennifer Dahne, Brian K. Chen, Tracy T. Smith, Amy E. Wahlquist and Mathew J. Carpenter

Published online by Cambridge University Press:  20 April 2023

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Design and implementation of a digital site-less clinical study of serial rapid antigen testing to identify asymptomatic SARS-CoV-2 infection

Apurv Soni, Carly Herbert, Caitlin Pretz, Pamela Stamegna, Andreas Filippaios, Qiming Shi, Thejas Suvarna, Emma Harman, Summer Schrader, Chris Nowak, Eric Schramm, Vik Kheterpal, Stephanie Behar, Seanan Tarrant, Julia Ferranto, Nathaniel Hafer, Matthew Robinson, Chad Achenbach, Robert L. Murphy, Yukari C. Manabe, Laura Gibson, Bruce Barton, Laurel O’Connor, Nisha Fahey, Elizabeth Orvek, Peter Lazar, Didem Ayturk, Steven Wong, Adrian Zai, Lisa Cashman, Lokinendi V. Rao, Katherine Luzuriaga, Stephenie Lemon, Allison Blodgett, Elizabeth Trippe, Mary Barcus, Brittany Goldberg, Kristian Roth, Timothy Stenzel, William Heetderks, John Broach and David McManus

Published online by Cambridge University Press:  10 May 2023

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Remote and semi-automated methods to conduct a decentralized randomized clinical trial

Teresa Cafaro, Patrick J. LaRiccia, Brigid Bandomer, Helen Goldstein, Tracy L. Brobyn, Krystal Hunter, Satyajeet Roy, Kevin Q. Ng, Ludmil V. Mitrev,  Alan Tsai, Denise Thwing, Mary Ann Maag, Myung K. Chung, and Noud van Helmond

Published online by Cambridge University Press:  07 June 2023

Perspectives

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Towards a conceptual framework for addressing state-level barriers to decentralized clinical trials in the U.S.

Stephanie J. Zawada, Kevin C. Ruff, Tara Sklar and Bart M. Demaerschalk

Published online by Cambridge University Press:  03 July 2023

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Special Communications

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Decentralized clinical trials in the trial innovation network: Value, strategies, and lessons learned

Daniel F. Hanley Jr, Gordon R. Bernard, Consuelo H. Wilkins, Harry P. Selker, Jamie P. Dwyer, J. Michael Dean, Daniel Kelly Benjamin Jr, Sarah E. Dunsmore, Salina P. Waddy, Kenneth L. Wiley Jr, Marisha E. Palm, W. Andrew Mould, Daniel F. Ford, Jeri S. Burr, Jacqueline Huvane, Karen Lane, Lori Poole, Terri L. Edwards, Nan Kennedy, Leslie R. Boone, Jasmine Bell, Emily Serdoz, Loretta M. Byrne, and Paul A. Harris

Published online by Cambridge University Press:  25 July 2023

Research Article

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From a decentralized clinical trial to a decentralized and clinical-trial-in-a-box platform: Towards patient-centric and equitable trials

Dorothy Dulko, Manlik Kwong, Marisha E. Palm, Ludovic Trinquart and Harry P. Selker

Published online by Cambridge University Press:  09 October 2023

Review Article

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Methods and perceptions of success for patient recruitment in decentralized clinical studies

Brian L. Miyata, Barbara Tafuto, and Nadina Jose

Published online by Cambridge University Press:  06 October 2023

Special Communications

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ACTIV-6: Operationalizing a decentralized, outpatient randomized platform trial to evaluate efficacy of repurposed medicines for COVID-19

Published online by Cambridge University Press:  31 October 2023

The Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group

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Strategies used for the COVID-OUT decentralized trial of outpatient treatment of SARS-CoV-2

Nandini Avula, Dustin Kakach, Christopher J. Tignanelli, David M. Liebovitz, Jacinda M. Nicklas, Kenneth Cohen, Michael A. Puskarich, Hrishikesh K. Belani, John B. Buse, Nichole R. Klatt, Blake Anderson, Amy B. Karger, Katrina M. Hartman, Barkha Patel, Sarah L. Fenno, Neha V. Reddy, Spencer M. Erickson, David R. Boulware, Thomas A. Murray, Carolyn T. Bramante and COVID-OUT Trial Team

Published online by Cambridge University Press:  07 November 2023

Research Article

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The ACTIV-6 Stakeholder Advisory Committee: a model for virtual engagement in decentralized clinical trials

Megan E. Hamm, Jonathan Arnold, Josh Denson, Talethia Edwards, Greg Merritt, Matthew McCarthy, Danielle Nelson, Kirk T. Phillips, Florence Thicklin, Andrew Vasey and Kathleen McTigue

Published online by Cambridge University Press:  20 November 2023

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Decentralized research technology use in multicenter clinical research studies based at U.S. academic research centers

Mollie R. Cummins, Jeri Burr, Lisa Young, Sharon D. Yeatts, Dixie J. Ecklund, Brian E. Bunnell, Jamie P. Dwyer and John M. VanBuren

Published online by Cambridge University Press:  08 November 2023

Review Article

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Narrative review of telemedicine applications in decentralized research

Mollie R. Cummins, Hiral Soni, Julia Ivanova, Tritan Ong, Janelle Barrera, Hattie Wilczewski, Brandon Welch and Brian E. Bunnell

Published online by Cambridge University Press:  22 January 2024