Chapter 2, ‘The Embodied Letter’, examines the embodied consciousness in selected letters of the writers and painters. Drawing on critical thought in the medical humanities and in sensory studies, the chapter investigates the epistolary articulacy of body and mind through modes that span the documentary and the fantastic. First, the work of the sensorium is explored through the epistolary entanglement of the senses – from touch and taste to kinesthetics and proprioception. The chapter examines epistolary representations of wellbeing and illness, stories of embarrassing bodies, chronicles of everyday ‘troubles’, and the letterish discussion of public health, self-care, work, and leisure. The preoccupation with mental health and mental illness comes sharply into relief in epistolary evocations of boredom, exasperation, and depression, and their physical manifestations. Whilst such instances echo nineteenth-century literary evocations of spleen, they speak powerfully to some of our pressing contemporary concerns. End-of-life letters reveal a profound engagement with finitude through fragmentary narratives of struggle, separation, and mourning threaded with sustaining resilience.