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Transdiagnostic efficacy of lurasidone on depressive symptoms: systematic review and meta-analysis of randomised controlled trials: commentary, Chen et al

Published online by Cambridge University Press:  17 October 2025

Yang-Chieh Brian Chen Open the ORCID record for Yang-Chieh Brian Chen [Opens in a new window] ,
Chih-Sung Liang Open the ORCID record for Chih-Sung Liang [Opens in a new window] ,
Ping-Tao Tseng Open the ORCID record for Ping-Tao Tseng [Opens in a new window]  and
Chih-Wei Hsu Open the ORCID record for Chih-Wei Hsu [Opens in a new window]
Yang-Chieh Brian Chen
Affiliation:
Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, Houston, Texas, USA
Chih-Sung Liang
Affiliation:
Department of Psychiatry, Beitou Branch, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan Department of Psychiatry, National Defense Medical University, Taipei, Taiwan
Ping-Tao Tseng
Affiliation:
Prospect Clinic for Otorhinolaryngology and Neurology, Kaohsiung, Taiwan Institute of Biomedical Sciences, National Sun Yat-sen University, Kaohsiung, Taiwan Department of Psychology, College of Medical and Health Science, Asia University, Taichung, Taiwan Institute of Precision Medicine, National Sun Yat-sen University, Kaohsiung City, Taiwan
Chih-Wei Hsu*
Affiliation:
Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan
*
Correspondence: Chih-Wei Hsu. Email: harwicacademia@gmail.com
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Abstract

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Keywords

Depressiondose–responselurasidonepsychosis

Information

Type
Commentary
Information
The British Journal of Psychiatry , First View , pp. 1 - 2
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Copyright
© The Author(s), 2025. Published by Cambridge University Press on behalf of Royal College of Psychiatrists

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Footnotes

*

Joint first authors.

References

Ghenciulescu, A, Pearse, A, Minichino, A, Sampogna, G, De Giorgi, R, Fiorillo, A. Transdiagnostic efficacy of lurasidone on depressive symptoms: systematic review and meta-analysis of randomised controlled trials. Br J Psychiatry [Epub ahead of print] 20 Aug 2025. Available from: https://doi.org/10.1192/bjp.2025.10343.CrossRefGoogle Scholar
Lin, YW, Chen, YB, Hung, KC, Liang, CS, Tseng, PT, Carvalho, AF, et al. Efficacy and acceptability of lurasidone for bipolar depression: a systematic review and dose-response meta-analysis. BMJ Ment Health 2024; 27: e301165.10.1136/bmjment-2024-301165CrossRefGoogle ScholarPubMed
Srisurapanont, M, Suttajit, S, Likhitsathian, S, Maneeton, B, Maneeton, N. A network meta-analysis of the dose-response effects of lurasidone on acute schizophrenia. Sci Rep 2021; 11: 5571.10.1038/s41598-021-84836-zCrossRefGoogle ScholarPubMed
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