Hostname: page-component-7f64f4797f-l842n Total loading time: 0 Render date: 2025-11-04T05:03:18.886Z Has data issue: false hasContentIssue false
  • English
  • Français

A Psychiatric Investigation of Triple-X Chromosome Females

Published online by Cambridge University Press:  29 January 2018

Cecil B. Kidd ,
R. S. Knox  and
D. J. Mantle
Cecil B. Kidd
Affiliation:
Medical Research Council Unit for Research on the Epidemiology of Psychiatric Illness, Department of Psychological Medicine, University of Edinburgh
R. S. Knox
Affiliation:
Medical Research Council Unit for Research on the Epidemiology of Psychiatric Illness, Department of Psychological Medicine, University of Edinburgh
D. J. Mantle
Affiliation:
Medical Research Council, Research Unit on Clinical Effects of Radiation, Western General Hospital, Edinburgh
Get access Rights & Permissions [Opens in a new window]

Extract

Among recent developments in human chromosome studies a triple-X state has been recognized in females in whom the chromosome number is 47, composed of 44 autosomes and 3 X chromosomes (Jacobs et al., 1959). Early surveys of nuclear sex have shown that the triple-X state is a not uncommon chromosomal anomaly. A survey of Edinburgh babies gave a frequency at birth of these abnormal females of 1.78/1,000 births (Court Brown, 1962) and by combining data of surveys from Edinburgh (Maclean et al., 1962), Glasgow (Fraser et al., 1960) and Baltimore (Johnston et al., 1961) the estimated frequency of the triple-X state in mental subnormality institutions is 4.51/1,000 in-patients.

Information

Type
Research Article
Information
The British Journal of Psychiatry , Volume 109 , Issue 458 , January 1963 , pp. 90 - 94
Copyright
Copyright © Royal College of Psychiatrists, 1963 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Article purchase

Temporarily unavailable

References

Beckett, P. G. S., Senf, R., and Ax, A. (1956). Psychiatric Information Sheets. Detroit: Lafayette Clinic.Google Scholar
Curran, D., and Partridge, M. (1957). Psychological Medicine, 4th Ed. Edinburgh and London: Livingstone.Google Scholar
Court Brown, W. M. (1962). In Cytogenetics in Medicine, R.C.P.E., No. 18.Google Scholar
Fraser, J. H., Campbell, J., MacGillivray, R. C., Boyd, E., and Lennox, B. (1960). Lancet, ii, 626.Google Scholar
Jacobs, P. A., Baikie, A. G., Court Brown, W. M., MacGregor, T. N., Maclean, N., and Harnden, D. G. (1959). Lancet, ii, 423.Google Scholar
Johnston, A. W., Ferguson-Smith, M. A., Handmaker, S. D., Jones, H. W., and Jones, G. S. (1961). Brit. med. J., ii, 1046.Google Scholar
Maclean, N., Mitchell, J. M., Harnden, D. G., Williams, J., Jacobs, P. A., Buckton, K. A., Baikie, A. G., Court Brown, W. M., McBride, J. A., Strong, J. A., Close, H. G., and Jones, D. C. (1962). Lancet, i, 293.Google Scholar
Wing, J. K. (1960). Acta Psychiat. et Neurol. Scand., 35, Fasc. 2.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.