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A Biochemical Study of Short-Cycle Manic-Depressive Psychosis in Mental Defectives

Published online by Cambridge University Press:  29 January 2018

Graham J. Naylor ,
Andrew H. Reid ,
David A. T. Dick  and
Elizabeth G. Dick
Graham J. Naylor
Affiliation:
Department of Psychiatry, The University, Dundee
Andrew H. Reid
Affiliation:
Royal Dundee Liff Hospital, By Dundee
David A. T. Dick
Affiliation:
Department of Anatomy, The University, Dundee
Elizabeth G. Dick
Affiliation:
Department of Anatomy, The University, Dundee
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Summary

Four mentally defective patients who were suffering from short-cycle manic-depressive psychosis were each studied under metabolic ward conditions for about six months. Weekly estimations of erythrocyte Na-K ATPase activity, ouabain sensitive potassium influx, sodium concentration, whole blood cell ATP concentration and blood haematocrit were made. The findings in each patient differed, but the erythrocyte Na-K ATPase activity, sodium and ATP concentration appeared to show cyclic changes related to, though out of phase with, the clinical state.

Information

Type
Research Article
Information
The British Journal of Psychiatry , Volume 128 , Issue 2 , February 1976 , pp. 169 - 180
Copyright
Copyright © Royal College of Psychiatrists, 1976 

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