Hostname: page-component-cb9f654ff-k7rjm Total loading time: 0 Render date: 2025-09-03T17:09:30.656Z Has data issue: false hasContentIssue false

Laryngocele: diagnosis, management and association with laryngeal cancer

Published online by Cambridge University Press:  25 March 2025

Xiaxia Li
Affiliation:
Department of Otorhinolaryngology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, ZJ, China
Zhewei Lou
Affiliation:
Department of Otorhinolaryngology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, ZJ, China
Zhihong Lin*
Affiliation:
Department of Otorhinolaryngology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, ZJ, China
*
Corresponding author: Zhihong Lin; Email: 2189007@zju.edu.cn

Abstract

Objectives

This article aimed to summarize the clinical characteristics and our experience with the diagnosis and management of laryngocele. We offer our perspectives for cases associated with laryngeal cancer.

Methods

A retrospective study of 14 patients with laryngocele was accomplished from June 2014 to June 2024. Clinical data were analyzed through descriptive statistical methods.

Results

A total of 14 laryngocele patients were divided into internal type (n = 11; 78.6 per cent) and combined type (n = 3; 21.4 per cent). Nine laryngocele patients (n = 9; 64.3 per cent) were accompanied by laryngeal cancer. The transoral approach was applied in 11 internal laryngocele patients with no post-operative complications or recurrences.

Conclusion

Laryngoscopy and imaging examination are helpful for diagnosis especially to exclude laryngeal cancer. The transoral approach is effective for the internal type, and the key is to resect the anterior part of the false vocal fold. For patients with concomitant laryngeal cancer, the laryngocele should be promptly managed.

Information

Type
Main Article
Copyright
© The Author(s), 2025. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED.

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Article purchase

Temporarily unavailable

Footnotes

Zhihong Lin takes responsibility for the integrity of the content of the paper

References

Stell, PM, Maran, AG. Laryngocoele. J Laryngol Otol 1975;89:915–24CrossRefGoogle ScholarPubMed
Verret, DJ, DeFatta, RJ, Sinard, R. Combined laryngocele. Ann Otol Rhinol Laryngol 2004;113:594–6CrossRefGoogle ScholarPubMed
James, DL, Garry, S, Corbett, M, Lang, J. Mixed infected laryngocoele presenting as airway obstruction: a case report. J Surg Case Rep 2021;2021:rjaa615CrossRefGoogle ScholarPubMed
Zelenik, K, Stanikova, L, Smatanova, K, Cerny, M, Kominek, P. Treatment of laryngoceles: what is the progress over the last two decades? Biomed Res Int 2014;2014:819453CrossRefGoogle Scholar
Micheau, C, Luboinski, B, Lanchi, P, Cachin, Y. Relationship between laryngoceles and laryngeal carcinomas. Laryngoscope 1978;88:680–8CrossRefGoogle ScholarPubMed
Celin, SE, Johnson, J, Curtin, H, Barnes, L. The association of laryngoceles with squamous cell carcinoma of the larynx. Laryngoscope 1991;101:529–36CrossRefGoogle ScholarPubMed
Close, LG, Merkel, M, Burns, DK, CW, Deaton Jr, Schaefer, SD. Asymptomatic laryngocele: incidence and association with laryngeal cancer. Ann Otol Rhinol Laryngol 1987;96:393–9CrossRefGoogle Scholar
Myssiorek, D, Madnani, D, Delacure, MD. The external approach for submucosal lesions of the larynx. Otolaryngol Head Neck Surg 2001;125:370–3CrossRefGoogle ScholarPubMed
Purnell, PR, Haught, E, Turner, MT. Minimally invasive treatment of laryngoceles: a systematic review and pooled analysis. J Robot Surg 2022;16:114CrossRefGoogle ScholarPubMed
Heuveling, DA, Mahieu, HF. Endoscopic CO2 laser resection using the inversion technique in 22 combined laryngoceles. Laryngoscope 2023;133:2742–6CrossRefGoogle ScholarPubMed
Virchow, R. Die krankhaften Geschwülste. Hirschwald: 1867Google Scholar
Holinger, LD, Barnes, DR, Smid, LJ, Holinger, PH. Laryngocele and saccular cysts. Ann Otol Rhinol Laryngol 1978;87:675–85CrossRefGoogle ScholarPubMed
Mobashir, MK, Basha, WM, Mohamed, AE, Hassaan, M, Anany, AM. Laryngoceles: concepts of diagnosis and management. Ear Nose Throat J 2017;96:133–8CrossRefGoogle ScholarPubMed
Macfie, DD. Asymptomatic laryngoceles in wind-instrument bandsmen. Arch Otolaryngol 1966;83:270–5CrossRefGoogle ScholarPubMed
Marom, T, Roth, Y, Cinamon, U. Laryngocele: a rare long-term complication following neck surgery? J Voice 2011;25:272–4CrossRefGoogle ScholarPubMed
Dhaha, M, Jbali, S, Dhambri, S, Mahjoub, M, Touati, S, Gritli, S. Laryngocele after subtotal laryngectomy. Iran J Otorhinolaryngol 2018;30:305–8Google ScholarPubMed
Slonimsky, E, Goldenberg, D, Hwang, G, Gagnon, E, Slonimsky, G. A comprehensive update of the incidence and demographics of laryngoceles in adults. Ann Otol Rhinol Laryngol 2022;131:1078–84CrossRefGoogle ScholarPubMed
Alvi, A, Weissman, J, Myssiorek, D, Narula, S, Myers, EN. Computed tomographic and magnetic resonance imaging characteristics of laryngocele and its variants. Am J Otolaryngol 1998;19:251–6CrossRefGoogle ScholarPubMed
El-Naggar, A, Abdelaziz, M, Mandour, MF. Thyroid chondroplastic flap for resection of laryngoceles. Eur Arch Otorhinolaryngol 2021;278:4477–81CrossRefGoogle ScholarPubMed