Hostname: page-component-65b85459fc-hn4tn Total loading time: 0 Render date: 2025-10-16T04:26:31.483Z Has data issue: false hasContentIssue false
  • English
  • Français

Prognostic Significance of CRP, BMI, and Ferritin Levels in Predicting COVID-19 Outcomes in Psychiatric Patients: A Comparative Analysis

Published online by Cambridge University Press:  26 August 2025

K. Argyropoulos ,
A.-A. Argyropoulou-Grizanou ,
P. Gourzis  and
E. Jelastopulu
K. Argyropoulos
Affiliation:
Public Health, School of Medicine, University of Patras, Patras
A.-A. Argyropoulou-Grizanou
Affiliation:
Social Sciences, Hellenic Open University, Athens
P. Gourzis*
Affiliation:
Psychiatry, School of Medicine, University of Patras, Patras, Greece
E. Jelastopulu
Affiliation:
Public Health, School of Medicine, University of Patras, Patras
*
*Corresponding author.

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Introduction

This study investigates the predictive value of ferritin, CRP, and BMI levels in predicting COVID-19 outcomes among psychiatric patients.

Objectives

Understanding these markers is crucial given the increased vulnerability of psychiatric patients to severe COVID-19 outcomes.

Methods

We conducted a retrospective analysis of 100 psychiatric patients diagnosed with COVID-19. We collected clinical outcomes (survival or death) data, demographic characteristics, and comorbidities. Blood samples were analyzed for ferritin and CRP levels, and BMI was calculated based on recorded weight and height. Statistical tests, including t-tests and chi-square tests, were used to assess the relationships between these variables and COVID-19 outcomes. Survival analysis was performed using the Log-Rank test to evaluate the impact of these markers on patient survival.

Results

Our results showed that higher ferritin levels were significantly associated with poorer outcomes, with survivors having a mean ferritin level of 246.2 (SD = 150.3) compared to 416.9 (SD = 215.9) in non-survivors (p < 0.001). Similarly, mean CRP levels were lower in survivors (1.58, SD = 1.96) compared to non-survivors (3.46, SD = 2.92) with a p-value of 0.002. BMI did not show a statistically significant difference between survivors and non-survivors (p = 0.429). Survival analysis revealed that elevated CRP and ferritin levels correlated with decreased survival rates.

Conclusions

The study highlights the significant role of ferritin and CRP as prognostic markers in psychiatric patients with COVID-19, suggesting that elevated levels of these biomarkers are associated with worse outcomes. However, BMI did not significantly affect survival, indicating that inflammatory markers might be more relevant for assessing prognosis in this population. These findings emphasize the need for vigilant monitoring of these biomarkers in psychiatric patients to manage their COVID-19 treatment better and improve outcomes.

Disclosure of Interest

None Declared

Information

Type
Abstract
Information
European Psychiatry , Volume 68 , Special Issue S1: Abstracts of the 33rd European Congress of Psychiatry , April 2025 , pp. S621
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2025. Published by Cambridge University Press on behalf of European Psychiatric Association
Submit a response

Comments

No Comments have been published for this article.