This work is concerned with the exponential turnpike property for optimal control problems of particle systems and their mean-field limit. Under the assumption of the strict dissipativity of the cost function, exponential estimates for both optimal states and optimal control are proven. Moreover, we show that all the results for particle systems can be preserved under the limit in the case of infinitely many particles.

This paper studies the spatio-temporal dynamics of a diffusive plant-sulphide model with toxicity delay. More specifically, the effects of discrete delay and distributed delay on the dynamics are explored, respectively. The deep analysis of eigenvalues indicates that both diffusion and delay can induce Hopf bifurcations. The normal form theory is used to set up an exact formula that determines the properties of Hopf bifurcation in a diffusive plant-sulphide model. A sufficiently small discrete delay does not affect the stability and a sufficiently large discrete delay destabilizes the system. Nonetheless, a sufficiently small or large distributed delay does not affect the stability. Both delays cause instability by inducing Hopf bifurcation rather than Turing bifurcation.

The purpose of this paper is to derive anisotropic mean curvature flow as the limit of the anisotropic Allen–Cahn equation. We rely on distributional solution concepts for both the diffuse and sharp interface models and prove convergence using relative entropy methods, which have recently proven to be a powerful tool in interface evolution problems. With the same relative entropy, we prove a weak–strong uniqueness result, which relies on the construction of gradient flow calibrations for our anisotropic energy functionals.

This work describes a hyperbolic model for cell-cell repulsion with population dynamics. We consider the pressure produced by a population of cells to describe their motion. We assume that cells try to avoid crowded areas and prefer locally empty spaces far away from the carrying capacity. Here, our main goal is to prove the existence of travelling waves with continuous profiles. This article complements our previous results about sharp travelling waves. We conclude the paper with numerical simulations of the PDE problem, illustrating such a result. An application to wound healing also illustrates the importance of travelling waves with a continuous and discontinuous profile.

Precise knowledge of magnetic fields is crucial in many medical imaging applications such as magnetic resonance imaging (MRI) or magnetic particle imaging (MPI), as they form the foundation of these imaging systems. Mathematical methods are essential for efficiently analysing the magnetic fields in the entire field-of-view. In this work, we propose a compact and unique representation of the magnetic fields using real solid spherical harmonic expansions, which can be obtained by spherical t-designs. To ensure a unique representation, the expansion point is shifted at the level of the expansion coefficients. As an application scenario, these methods are used to acquire and analyse the magnetic fields of an MPI system. Here, the field-free-point of the spatial encoding field serves as the unique expansion point.

We address the problem of optimal transport with a quadratic cost functional and a constraint on the flux through a constriction along the path. The constriction, conceptually represented by a toll station, limits the flow rate across. We provide a precise formulation which, in addition, is amenable to generalization in higher dimensions. We work out in detail the case of transport in one dimension by proving existence and uniqueness of solution. Under suitable regularity assumptions, we give an explicit construction of the transport plan. Generalization of flux constraints to higher dimensions and possible extensions of the theory are discussed.

Consensus-based optimisation (CBO) is a versatile multi-particle metaheuristic optimisation method suitable for performing non-convex and non-smooth global optimisations in high dimensions. It has proven effective in various applications while at the same time being amenable to a theoretical convergence analysis. In this paper, we explore a variant of CBO, which incorporates truncated noise in order to enhance the well-behavedness of the statistics of the law of the dynamics. By introducing this additional truncation in the noise term of the CBO dynamics, we achieve that, in contrast to the original version, higher moments of the law of the particle system can be effectively bounded. As a result, our proposed variant exhibits enhanced convergence performance, allowing in particular for wider flexibility in choosing the noise parameter of the method as we confirm experimentally. By analysing the time evolution of the Wasserstein-$2$ distance between the empirical measure of the interacting particle system and the global minimiser of the objective function, we rigorously prove convergence in expectation of the proposed CBO variant requiring only minimal assumptions on the objective function and on the initialisation. Numerical evidences demonstrate the benefit of truncating the noise in CBO.

We introduce a free boundary model to study the effect of vesicle transport onto neurite growth. It consists of systems of drift-diffusion equations describing the evolution of the density of antero- and retrograde vesicles in each neurite coupled to reservoirs located at the soma and the growth cones of the neurites, respectively. The model allows for a change of neurite length as a function of the vesicle concentration in the growth cones. After establishing existence and uniqueness for the time-dependent problem, we briefly comment on possible types of stationary solutions. Finally, we provide numerical studies on biologically relevant scales using a finite volume scheme. We illustrate the capability of the model to reproduce cycles of extension and retraction.

All vital functions of living cells rely on the production of various functional molecules through gene expression. The production periods are burst-like and stochastic due to the discrete nature of biochemical reactions. In certain contexts, the concentrations of RNA or protein require regulation to maintain a fine internal balance within the cell. Here we consider a motif of two types of RNA molecules – mRNA and an antagonistic microRNA – which are encoded by a shared coding sequence and form a feed forward loop (FFL). This control mechanism is shown to be perfectly adapting in the deterministic context. We demonstrate that the adaptation (of the mean value) becomes imperfect if production occurs in random bursts. The FFL nevertheless outperforms the benchmark feedback loop in terms of counterbalancing variations in the signal. Methodologically, we adapt a hybrid stochastic model, which has widely been used to model a single regulatory molecule, to the current case of a motif involving two species; the use of the Laplace transform thereby circumvents the problem of moment closure that arises owing to the mRNA–microRNA interaction. We expect that the approach can be applicable to other systems with nonlinear kinetics.

This article studies the dynamical behaviour of classical solutions of a hyperbolic system of balance laws, derived from a chemotaxis model with logarithmic sensitivity, with time-dependent boundary conditions. It is shown that under suitable assumptions on the boundary data, solutions starting in the $H^2$-space exist globally in time and the differences between the solutions and their corresponding boundary data converge to zero as time goes to infinity. There is no smallness restriction on the magnitude of the initial perturbations. Moreover, numerical simulations show that the assumptions on the boundary data are necessary for the above-mentioned results to hold true. In addition, numerical results indicate that the solutions converge asymptotically to time-periodic states if the boundary data are time-periodic.

In this paper, we study the existence of travelling wave solutions and the spreading speed for the solutions of an age-structured epidemic model with nonlocal diffusion. Our proofs make use of the comparison principles both to construct suitable sub/super-solutions and to prove the regularity of travelling wave solutions.

We propose and unify classes of different models for information propagation over graphs. In a first class, propagation is modelled as a wave, which emanates from a set of known nodes at an initial time, to all other unknown nodes at later times with an ordering determined by the arrival time of the information wave front. A second class of models is based on the notion of a travel time along paths between nodes. The time of information propagation from an initial known set of nodes to a node is defined as the minimum of a generalised travel time over subsets of all admissible paths. A final class is given by imposing a local equation of an eikonal form at each unknown node, with boundary conditions at the known nodes. The solution value of the local equation at a node is coupled to those of neighbouring nodes with lower values. We provide precise formulations of the model classes and prove equivalences between them. Finally, we apply the front propagation models on graphs to semi-supervised learning via label propagation and information propagation on trust networks.

This paper is concerned with the development and analysis of a mathematical model that is motivated by interstitial hydrodynamics and tissue deformation mechanics (poro-elasto-hydrodynamics) within an in-vitro solid tumour. The classical mixture theory is adopted for mass and momentum balance equations for a two-phase system. A main contribution of this study is we treat the physiological transport parameter (i.e., hydraulic resistivity) as anisotropic and heterogeneous, thus the governing system is strongly coupled and non-linear. We derived a weak formulation and then formulated the equivalent fixed-point problem. This enabled us to use the Galerkin method, and the classical results on monotone operators combined with the well-known Schauder and Banach fixed-point theorems to prove the existence and uniqueness of results.

Measuring inequalities in a multidimensional framework is a challenging problem, which is common to most field of science and engineering. Nevertheless, despite the enormous amount of researches illustrating the fields of application of inequality indices, and of the Gini index in particular, very few consider the case of a multidimensional variable. In this paper, we consider in some details a new inequality index, based on the Fourier transform, that can be fruitfully applied to measure the degree of inhomogeneity of multivariate probability distributions. This index exhibits a number of interesting properties that make it very promising in quantifying the degree of inequality in datasets of complex and multifaceted social phenomena.

We introduce a new non-abelian quantum synchronisation model over the unitary group, represented as a gradient flow, where state matrices asymptotically converge to a common one up to phase translation. We provide a sufficient framework leading to quantum synchronisation based on Riccati-type differential inequalities. In addition, uniform time-delayed interaction is considered for modelling realistic communication, and we demonstrate that quantum synchronisation is persistent when a small time delay is allowed. Finally, numerical simulation is performed to visualise qualitative behaviours and support theoretical results.

Coffee berry diseases (CBD) pose significant threats to coffee production worldwide, affecting the livelihoods of millions of farmers and the global coffee market. Fractional calculus provides a powerful framework for describing non-local and memory-dependent phenomena, making it suitable for modelling the long-range interactions inherent in CBD spread. This study aims to formulate and analyse fractional order model for CBD transmission dynamics in the sense of Atangana–Baleanu–Caputo. Fixed point theorems were utilised to test the existence and uniqueness of the model’s solutions using fractional order. The basic reproduction number was calculated utilising the next-generation matrix. The model has locally asymptotically stable equilibrium positions (disease-free and endemic). Furthermore, the Lyapunov function was used to conduct a global stability analysis of the equilibrium locations. A numerical simulation of the CBD model was created using the fractional Adam–Bashforth–Moulton approach to validate the analytical findings. Our findings contribute to the development of more accurate predictive models and inform the design of targeted interventions to mitigate the impact of CBD on coffee production systems.

We consider self-propelled rigid bodies interacting through local body-attitude alignment modelled by stochastic differential equations. We derive a hydrodynamic model of this system at large spatio-temporal scales and particle numbers in any dimension $n \geq 3$. This goal was already achieved in dimension $n=3$ or in any dimension $n \geq 3$ for a different system involving jump processes. However, the present work corresponds to huge conceptual and technical gaps compared with earlier ones. The key difficulty is to determine an auxiliary but essential object, the generalised collision invariant. We achieve this aim by using the geometrical structure of the rotation group, namely its maximal torus, Cartan subalgebra and Weyl group as well as other concepts of representation theory and Weyl’s integration formula. The resulting hydrodynamic model appears as a hyperbolic system whose coefficients depend on the generalised collision invariant.

We propose a new fractional Laplacian for bounded domains, expressed as a conservation law and thus particularly suited to finite-volume schemes. Our approach permits the direct prescription of no-flux boundary conditions. We first show the well-posedness theory for the fractional heat equation. We also develop a numerical scheme, which correctly captures the action of the fractional Laplacian and its anomalous diffusion effect. We benchmark numerical solutions for the Lévy–Fokker–Planck equation against known analytical solutions. We conclude by numerically exploring properties of these equations with respect to their stationary states and long-time asymptotics.

In this paper, we present a sufficient framework to exhibit the sample path-wise asymptotic flocking dynamics of the Cucker–Smale model with unit-speed constraint and the randomly switching network topology. We employ a matrix formulation of the given equation, which allows us to evaluate the diameter of velocities with respect to the adjacency matrix of the network. Unlike the previous result on the randomly switching Cucker–Smale model, the unit-speed constraint disallows the system to be considered as a nonautonomous linear ordinary differential equation on velocity vector, which forces us to get a weaker form of the flocking estimate than the result for the original Cucker–Smale model.