Hostname: page-component-cb9f654ff-d5ftd Total loading time: 0 Render date: 2025-08-27T19:59:52.708Z Has data issue: false hasContentIssue false

Paediatric coronary artery bypass grafting in a middle-income country: a case series and literature review

Published online by Cambridge University Press:  01 August 2025

Isabella Roa-Bastidas
Affiliation:
Cardiovascular Surgery Resident. Universidad del Rosario. School of Medicine and Health Sciences, Bogotá, Colombia
Tomás Chalela*
Affiliation:
Cardiovascular Surgery, Fundación Cardioinfantil - La Cardio, Bogotá, Colombia
Aura M. Rivera
Affiliation:
Cardiovascular Surgery, Fundación Cardioinfantil - La Cardio, Bogotá, Colombia
Albert F. Guerrero
Affiliation:
Cardiovascular Surgery, Fundación Cardioinfantil - La Cardio, Bogotá, Colombia
Carlos E. Obando
Affiliation:
Cardiovascular Surgery, Fundación Cardioinfantil - La Cardio, Bogotá, Colombia
Jaime Camacho
Affiliation:
Cardiovascular Surgery, Fundación Cardioinfantil - La Cardio, Bogotá, Colombia
Carlos A. Villa
Affiliation:
Cardiovascular Surgery, Fundación Cardioinfantil - La Cardio, Bogotá, Colombia
Andrés F. Jimenez
Affiliation:
Cardiovascular Surgery, Fundación Cardioinfantil - La Cardio, Bogotá, Colombia
Nestor Sandoval
Affiliation:
Cardiovascular Surgery, Fundación Cardioinfantil - La Cardio, Bogotá, Colombia
*
Corresponding author: Tomás Chalela; Email: tomascha@gmail.com

Abstract

Background:

Coronary artery abnormalities in children that require bypass grafting are infrequent but represent a well-recognised entity with a broad spectrum of indications beyond Kawasaki disease. Although myocardial revascularisation in children is uncommon, studies have shown that it can yield favourable short- and long-term outcomes, allowing affected children to regain health and grow up to live normal lives.

Myocardial revascularisation in children is an extremely rare intervention in Western countries, accounting for less than 1% of all paediatric cardiac surgeries in this region. It is a highly technically demanding procedure that opens a new arena in cardiac surgery, for which cardiovascular surgeons need to be trained to achieve outcomes as good as those shown in the literature.

We present the experience of paediatric coronary artery bypass grafting in a middle-income country, with a wide range of indications.

Methods:

A retrospective descriptive study was conducted on paediatric patients (under 18 years of age) who underwent coronary artery bypass grafting between 2004 and 2023 at a cardiovascular centre in Bogotá, Colombia. Data were collected from electronic medical records, including demographics, preoperative diagnoses, surgical details, and outcomes. Follow-up included clinical assessment and imaging with echocardiography. Ethical approval was obtained, and confidentiality was ensured.

Results:

Nine paediatric patients (ages 6–17) underwent coronary artery bypass grafting between 2004 and 2023. Kawasaki disease was the most common indication, but there are other aetiologies, including post-arterial switch coronary occlusion, anomalous origin of the LCA from the pulmonary artery, anomalous origin of coronary arteries from the aorta, Takayasu disease, and iatrogenic injury. The internal mammary artery was used in most cases, with successful completion of the planned revascularisation in all patients. There were no perioperative deaths or reinterventions. At a mean follow-up of 5.5 years, all patients showed clinical and biventricular improvement, and all grafts evaluated showed graft patency.

Paediatric coronary artery bypass grafting is a safe and effective treatment for selected congenital and acquired coronary pathologies, even in complex cases. Outcomes are optimised with the use of internal mammary arteries and a multidisciplinary heart team approach. In middle-income settings, favourable short- and mid-term results can be achieved despite follow-up challenges. Paediatric coronary artery bypass grafting should be considered a key component of congenital cardiac surgery training.

Information

Type
Original Article
Copyright
© The Author(s), 2025. Published by Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Article purchase

Temporarily unavailable

References

Bachar, BJ, Manna, B. Coronary Artery Bypass Graft. StatPearls; 2023,Google ScholarPubMed
Bolotin, G, Medalion, B, Ghandakly, EC, Iacona, GM, Bakaeen, FG. Coronary artery surgery: past, present, and future. Rambam Maimonides Med J 2024; 15: e0001. doi: 10.5041/RMMJ.10515.Google Scholar
Komarov, R, Ismailbaev, A, Chragyan, V, et al. State-of-the-art pediatric coronary artery bypass surgery: a literature review. Braz J Cardiovasc Surg 2020; 35: 539548. doi: 10.21470/1678-9741-2019-0366.CrossRefGoogle ScholarPubMed
Kitamura, S. A new arena in cardiac surgery: pediatric coronary artery bypass surgery. Proc Jpn Acad Ser B Phys Biol Sci 2018; 94: 119. doi: 10.2183/pjab.94.001.CrossRefGoogle ScholarPubMed
Arnaz, A, Sarioglu, T, Yalcinbas, Y, et al. Coronary artery bypass grafting in children. J Cardiac Surg 2018; 33: 2934. doi: 10.1111/jocs.13510.CrossRefGoogle ScholarPubMed
Kitamura, S, Tsuda, E, Kobayashi, J, et al. Twenty-five-year outcome of pediatric coronary artery bypass surgery for Kawasaki disease. Circulation 2009; 120: 6068. doi: 10.1161/CIRCULATIONAHA.108.840603.CrossRefGoogle ScholarPubMed
Vida, VL, Torregrossa, G, De Franceschi, M, et al. European Congenital Heart Surgeons Association (ECHSA). Pediatric coronary artery revascularization: a European multicenter study. Ann Thorac Surg 2013; 96: 898903. doi: 10.1016/j.athoracsur.2013.05.006.CrossRefGoogle ScholarPubMed
Thammineni, K, Vinocur, JM, Harvey, B, et al. Outcomes after surgical coronary artery revascularisation in children with congenital heart disease. Heart 2018; 104: 14171423. doi: 10.1136/heartjnl-2017-312652.CrossRefGoogle ScholarPubMed
Das, M, Narayan, P. Coronary artery bypass grafting in children for atheromatous and non-atheromatous lesions. Indian J Thorac Cardiovasc Surg 2021; 37: 155164. doi: 10.1007/s12055-020-00946-9.CrossRefGoogle ScholarPubMed
Edvardsen, T, Asch, FM, Davidson, B, et al. Non-invasive imaging in coronary syndromes: recommendations of The European Association of Cardiovascular Imaging and the American Society of Echocardiography Collaboration with The American Society of Nuclear Cardiology, Society of Cardiovascular Computed Tomography, and Society for Cardiovascular Magnetic Resonance. J Cardiovasc Comput Tomogr 2022; 16: 362383. doi: 10.1016/j.jcct.2022.05.006.CrossRefGoogle ScholarPubMed
Members Writing Committee: Lawton, JS, Tamis-Holland, JE, Bangalore, S et al. ACC/AHA/SCAI guideline for coronary artery revascularization: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. J Am Coll Cardiol 2021; 79: e21e129. DOI: 10.1016/j.jacc.2021.09.006.Epub 2021 Dec 9. Erratum in: J Am Coll Cardiol. 2022 Apr 2022-01. Erratum in: J Am Coll Cardiol. 2024 Aug,10.1016/j.jacc.2021.09.006CrossRefGoogle Scholar
Baumann Kreuziger, L, Karkouti, K, Tweddell, J, Massicotte, MP. Antithrombotic therapy management of adult and pediatric cardiac surgery patients. J Thromb Haemost 2018; 16: 21332146. doi: 10.1111/jth.14276.CrossRefGoogle ScholarPubMed