Published online by Cambridge University Press: 05 June 2014
Introduction
Cancer staging refers to the classification of patients based on the anatomic extent of disease. The Tumor Node Metastasis (TNM) classification evolved from the work of Pierre Denoix in the 1940s and has since been adopted as the reference standard by the International Union Against Cancer (Union Internationale Contre le Cancer – UICC) and the American Joint Committee on Cancer (AJCC). These two bodies collaborate to ensure a uniform TNM classification. The most recent classification, the seventh edition, was published in 2009. This revision contains the first changes since the 1997 fifth edition. The changes were based upon proposals submitted by the International Association for the Study of Lung Cancer (IASLC). The seventh edition will be used throughout this chapter, with reference to the sixth edition where necessary to highlight important changes.
The TNM Classification fulfills a number of related objectives, namely:
To aid the clinician in the planning of treatment.
To give some indication of prognosis.
To assist in evaluation of the results of treatment.
To facilitate the exchange of information between treatment centers.
To contribute to the continuing investigation of human cancer.
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