Skip to main content Accessibility help
×
Hostname: page-component-6bb9c88b65-xjl2h Total loading time: 0 Render date: 2025-07-25T05:54:50.865Z Has data issue: false hasContentIssue false

Chapter 44 - Rabies

from Section 6 - Viral Infections

Published online by Cambridge University Press:  18 June 2025

David Mabey
Affiliation:
London School of Hygiene and Tropical Medicine
Martin W. Weber
Affiliation:
World Health Organization
Moffat Nyirenda
Affiliation:
London School of Hygiene and Tropical Medicine
Dorothy Yeboah-Manu
Affiliation:
Noguchi Memorial Institute for Medical Research, University of Ghana
Jackson Orem
Affiliation:
Uganda Cancer Institute, Kampala
Laura Benjamin
Affiliation:
University College London
Michael Marks
Affiliation:
London School of Hygiene and Tropical Medicine
Nicholas A. Feasey
Affiliation:
Liverpool School of Tropical Medicine
Get access

Summary

Rabies is an almost invariably fatal encephalomyelitis, which is caused by the neurotropic rabies virus. It is entirely preventable by vaccination, but when signs and symptoms of rabies present, it is already too late to save a person’s life. Rabies can be controlled in humans and dogs, its main vector in Africa, using an overarching ‘one health’ approach (Octaria 2018).

Information

Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2025

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Book purchase

Temporarily unavailable

References

Awasthi, M., Parmar, H., Patankar, T. et al. (2001). Imaging findings in rabies encephalitis. Am J Neuroradiology, 22 (4): 677680.Google ScholarPubMed
Begeman, L., GeurtsvanKessel, C., Finke, S. et al. (2018). Comparative pathogenesis of rabies in bats and carnivores, and implications for spillover to humans. Lancet Inf Dis, 18(4): e147e159. doi: 10.1016/S1473-3099(17)30574-1.CrossRefGoogle ScholarPubMed
Burdon Bailey, J. L., Gamble, L., Gibson, A. D. et al. (2018). A rabies lesson improves rabies knowledge amongst primary school children in Zomba, Malawi. PLoS Negl Trop Dis, 12(3): e0006293. https://doi.org/10.1371/journal.pntd.0006293CrossRefGoogle ScholarPubMed
Howlett, W. P. (2015). Rabies. In Neurology in Africa, 141144. Cambridge: Cambridge University Press.CrossRefGoogle Scholar
Jibat, T., Hogeveen, H., Mourits, M. C. M. (2015). Review on dog rabies vaccination coverage in Africa: a question of dog accessibility or cost recovery? PLoS Negl Trop Dis, 9(2): e0003447. doi: 10.1371/journal.pntd.0003447.CrossRefGoogle ScholarPubMed
Lembo, T., Hampson, K., Haydon, D. T. et al. (2008). Exploring reservoir dynamics: a case study of rabies in the Serengeti ecosystem. J Appl Ecol, 45(4): 12461257. doi: 10.1111/j.1365-2664.2008.01468.x.CrossRefGoogle ScholarPubMed
Mallewa, M., Fooks, A. R., Banda, D. et al. (2007). Rabies encephalitis in malaria-endemic area, Malawi, Africa. Emerging Infectious Diseases, 13(1). doi: 10.3201/eid1301.060810.CrossRefGoogle ScholarPubMed
Mulipukwa, C. P., Mudenda, B., Mbewe, A. R. (2017). Insights and efforts to control rabies in Zambia: evaluation of determinants and barriers to dog vaccination in Nyimba district. PLoS Negl Trop Dis, 11(10): e0005946. doi.org/10.1371/journal.pntd.0005946.CrossRefGoogle ScholarPubMed
Octaria, R., Salyer, S. J., Blanton, J. et al. (2018). From recognition to action: a strategic approach to foster sustainable collaborations for rabies elimination. PLoS Negl Trop Dis, 12(10): e0006756. doi.org/10.1371/journal.pntd.0006756.CrossRefGoogle Scholar
Shim, E., Hampson, K., Cleaveland, S. et al. (2009). Evaluating the cost-effectiveness of rabies post-exposure prophylaxis: a case study in Tanzania. Vaccine, 27(51), 71677172. doi.org/10.1016/j.vaccine.2009.09.027.CrossRefGoogle ScholarPubMed
Swanepoel, R., Barnard, B. J., Meredith, C. D. et al. (1993). Rabies in southern Africa. J Vet Res, 60(4): 325346. PMID: 7777317.Google ScholarPubMed
Théordoidès, J. (1986). Histoire de la Rage. Cave canem. Paris: Masson.Google Scholar
Yizengawet, E., Tamyalew, G., Mulu, W. et al. (2018). Incidence of human rabies virus exposure in northwestern Amhara, Ethiopia. BMC Infectious Diseases, 18: 597. doi.org/10.1186/s12879-018-3500-3.CrossRefGoogle Scholar

Accessibility standard: Unknown

Accessibility compliance for the PDF of this book is currently unknown and may be updated in the future.

Save book to Kindle

To save this book to your Kindle, first ensure no-reply@cambridge-org.demo.remotlog.com is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×