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Chapter 36 - Leprosy

from Section 5 - Bacterial Infections

Published online by Cambridge University Press:  18 June 2025

David Mabey
Affiliation:
London School of Hygiene and Tropical Medicine
Martin W. Weber
Affiliation:
World Health Organization
Moffat Nyirenda
Affiliation:
London School of Hygiene and Tropical Medicine
Dorothy Yeboah-Manu
Affiliation:
Noguchi Memorial Institute for Medical Research, University of Ghana
Jackson Orem
Affiliation:
Uganda Cancer Institute, Kampala
Laura Benjamin
Affiliation:
University College London
Michael Marks
Affiliation:
London School of Hygiene and Tropical Medicine
Nicholas A. Feasey
Affiliation:
Liverpool School of Tropical Medicine
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Summary

Leprosy is a chronic disease predominantly affecting skin and nerves, which may result in disability and social stigma, creating problems for patients and their families. Africa is the third most affected region worldwide after Asia and South America (WHO 2020), reporting 20,205 new leprosy cases. In 2019, eight African countries still reported more than one new leprosy case per 10,000 population. There was a 17% reduction in case detection in Africa in 2020 with the onset of the COVID-19 pandemic (WHO 2021). The highest rate of advanced disability at diagnosis is reported in the African continent with 14.63% of newly diagnosed patients having Grade 2 Disability (WHO 2020). This not only implies delayed diagnosis, but increasing issues with disability, stigma and economic problems for individuals affected by leprosy.

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Publisher: Cambridge University Press
Print publication year: 2025

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