Skip to main content Accessibility help
×
Hostname: page-component-6bb9c88b65-s7dlb Total loading time: 0 Render date: 2025-07-24T13:45:56.206Z Has data issue: false hasContentIssue false

Chapter 73 - The Heart

from Section 11 - Diseases of Body Systems

Published online by Cambridge University Press:  18 June 2025

David Mabey
Affiliation:
London School of Hygiene and Tropical Medicine
Martin W. Weber
Affiliation:
World Health Organization
Moffat Nyirenda
Affiliation:
London School of Hygiene and Tropical Medicine
Dorothy Yeboah-Manu
Affiliation:
Noguchi Memorial Institute for Medical Research, University of Ghana
Jackson Orem
Affiliation:
Uganda Cancer Institute, Kampala
Laura Benjamin
Affiliation:
University College London
Michael Marks
Affiliation:
London School of Hygiene and Tropical Medicine
Nicholas A. Feasey
Affiliation:
Liverpool School of Tropical Medicine
Get access

Summary

Patterns of disease in Africa continue to change. An urban lifestyle limits traditional physical exercise and favours obesity. Moreover, the increase in cardiovascular risk factors, such as smoking, diabetes and coronary disease, are seen throughout the continent. Rheumatic heart disease is still far too prevalent, particularly among the poor; thus, these predisposing factors exacerbate the epidemiological transition from communicable to non-communicable disease. Nevertheless, there have been enormous technological advances in the last 10–20 years. For example, accessing clinical information from a phone in this digital era is now possible. The technology to diagnose and treat cardiac disease has also become more available and affordable: oximeters now only cost a few dollars, and electrocardiograms (ECGs) can be rapidly performed and automatically interpreted using a reusable belt, limiting the use of consumables. A tablet computer that does not require maintenance (Opio & Kellett 2017b) and bedside echocardiography is now widely available. Beta-blockers, angiotensin-converting enzyme inhibitors and angiotensin II receptor antagonists are widespread and affordable.

Information

Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2025

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Book purchase

Temporarily unavailable

References

Andy, J J, Ogunowo, P O et al. (1998). Helminth associated eosinophilia and tropical endomyocardial fibrosis (EMF) in Nigeria. Acta Trop 69: 127140.10.1016/S0001-706X(97)00125-3CrossRefGoogle ScholarPubMed
Arguedas, A & Mohs, E (1992). Prevention of rheumatic fever in Costa Rica. J Pediatr 121(4): 569572.10.1016/S0022-3476(05)81146-1CrossRefGoogle ScholarPubMed
Barillari, A, Barillari, G et al. (2011). Extended compression ultrasound performed by emergency physicians: a modified compression ultrasound examination to detect superficial and deep lower limb thromboses in the emergency department. J Med Ultrasound 19(103e108).10.1016/j.jmu.2011.08.005CrossRefGoogle Scholar
Bukhman, G, Ziegler, J et al. (2008). Endomyocardial fibrosis: still a mystery after 60 years. PLoS Negl Trop Dis 2(2): e97.10.1371/journal.pntd.0000097CrossRefGoogle Scholar
Freers, J, Masembe, V et al. (2000). Peritoneal fibrosis and muscle fibrosis are part of the endomyocardial fibrosis (EMF) syndrome. Lancet 355: 1994.10.1016/S0140-6736(05)72932-9CrossRefGoogle Scholar
Freers, J, Mayanja-Kizza, H et al. (1996). Endomyocardial fibrosis: why is there striking ascites with little or no peripheral oedema? Lancet 347: 197.10.1016/S0140-6736(96)90383-9CrossRefGoogle ScholarPubMed
Gewitz, MH, Baltimore, RS et al. (2015). Revision of the Jones Criteria for the diagnosis of acute rheumatic fever in the era of Doppler echocardiography: a scientific statement from the American Heart Association. Circulation 131(20): 18061818.10.1161/CIR.0000000000000205CrossRefGoogle Scholar
Hahn, D, Thomson, PD et al. (1998). A review of Takayasu’s arteritis in children in Gauteng, South Africa. Pediatr Nephrol 12(8): 668675.10.1007/s004670050526CrossRefGoogle ScholarPubMed
Johnson-Coyle, L, Jensen, L et al. (2012). Peripartum cardiomyopathy: review and practice guidelines. Am J Crit Care 21(2): 8998.10.4037/ajcc2012163CrossRefGoogle ScholarPubMed
Kingue, S, Kamdaju, R et al. (1999). Pronostic de la cardiomyopathic dilatée chez le noir africain de l’insuffisance cardiaque. Cardiol Trop 25: 4953.Google Scholar
Kline, JA, Courtney, DM et al. (2008). Prospective multicenter evaluation of the pulmonary embolism rule-out criteria. J Thromb Haemost 6(5): 772780.10.1111/j.1538-7836.2008.02944.xCrossRefGoogle ScholarPubMed
Marijon, E, Ou, P et al. (2007). Prevalence of rheumatic heart disease detected by echocardiographic screening. N Engl J Med 357(5): 470476.10.1056/NEJMoa065085CrossRefGoogle ScholarPubMed
Mayanja-Kizza, H, Gerwing, E et al. (2000). Tropical endomyocardial fibrosis in Uganda: the tribal and geographic distribution, and the association with eosinophilia. Trop Cardiol 103: 4548.Google Scholar
Mayosi, BM (2007). Contemporary trends in the epidemiology and management of cardiomyopathy and pericarditis in sub-Saharan Africa. Heart 93(10): 1176–83. doi: 10.1136/hrt.2007.127746.CrossRefGoogle ScholarPubMed
Mayosi, BM and Scott, Millar RN (2000). Permanent cardiac pacing in South Africa. East Afr Med J 77(6): 339.Google ScholarPubMed
Messias-Reason, IJ, Hayashi, SY et al. (2002). Complement activation in infective endocarditis: correlation with extracardiac manifestations and prognosis. Clin Exp Immunol 127(2): 310315.10.1046/j.1365-2249.2002.01772.xCrossRefGoogle ScholarPubMed
Mocumbi, AO, Ferreira, MB et al. (2008). A population study of endomyocardial fibrosis in a rural area of Mozambique. N Engl J Med 359(1): 4349.10.1056/NEJMoa0708629CrossRefGoogle Scholar
Opio, M O & Kellett, J (2017a). How well are pulses measured? practice-based evidence from an observational study of acutely ill medical patients during hospital admission. Am J Med 130(7): 863 e813863 e816.10.1016/j.amjmed.2017.01.033CrossRefGoogle ScholarPubMed
Opio, M O & Kellett, J (2017b). An observational study of the quality of ECGs recorded by inexperienced staff in a resource-poor African hospital using a reusable ECG belt linked to an internet ECG device. Eur J Intern Med 42: e17e18.10.1016/j.ejim.2017.04.004CrossRefGoogle Scholar
Rees, DC, Williams, TN et al. (2010). Sickle cell disease. Lancet 376: 20182031.10.1016/S0140-6736(10)61029-XCrossRefGoogle ScholarPubMed
Regitz-Zagrosek, V, Roos-Hesselink, J W et al. (2018). 2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy. Eur Heart J 39(34): 31653241.10.1093/eurheartj/ehy340CrossRefGoogle ScholarPubMed
Rimbi, M, Dunsmuir, D et al. (2019). Respiratory rates observed over 15 and 30 s compared with rates measured over 60 s: practice-based evidence from an observational study of acutely ill adult medical patients during hospital admission. QJM 112(7): 513517.10.1093/qjmed/hcz065CrossRefGoogle ScholarPubMed
Rutakingirwa, M, Ziegler, JL et al. (1999). Poverty and eosinophilia are risk factors for endomyocardial fibrosis (EMF) in Uganda. Trop Med Int Health 4: 229235.10.1046/j.1365-3156.1999.43376.xCrossRefGoogle ScholarPubMed
Stewart, S, Wilkinson, D et al. (2008). Predominance of heart failure in the Heart of Soweto Study cohort: emerging challenges for urban African communities. Circulation 118(23): 23602367.10.1161/CIRCULATIONAHA.108.786244CrossRefGoogle ScholarPubMed
Wells, PS, Anderson, DR et al. (2003). Evaluation of D-dimer in the diagnosis of suspected deep-vein thrombosis. N Engl J Med 349(13): 12271235.10.1056/NEJMoa023153CrossRefGoogle ScholarPubMed
White, RH & Keenan, CR (2009). Effects of race and ethnicity on the incidence of venous thromboembolism. Thromb Res 123 Suppl. 4: S1117.10.1016/S0049-3848(09)70136-7CrossRefGoogle ScholarPubMed
Wragg, A & Strang, J I (2000). Tuberculous pericarditis and HIV infection. Heart 84(2): 127128.10.1136/heart.84.2.127CrossRefGoogle ScholarPubMed
Wyber, R, Johnson, T et al. (2018). Tools for Implementing Rheumatic Heart Disease Control Progammes (TIPs) Handbook. 2nd ed. Geneva: RHD Action.Google Scholar
Zuhlke, L, Karthikeyan, G et al. (2016). Clinical outcomes in 3343 children and adults with rheumatic heart disease from 14 low- and middle-income countries: two-year follow-up of the Global Rheumatic Heart Disease Registry (the REMEDY Study). Circulation 134(19): 14561466.10.1161/CIRCULATIONAHA.116.024769CrossRefGoogle ScholarPubMed

Accessibility standard: Unknown

Accessibility compliance for the PDF of this book is currently unknown and may be updated in the future.

Save book to Kindle

To save this book to your Kindle, first ensure no-reply@cambridge-org.demo.remotlog.com is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×