Hypoglycemic patients are often hospitalized for further management. Most of these patients can be successfully managed in an observation unit (OU). OU management includes determining the cause of the hypoglycemia, lab tests (basic metabolic panel and renal function, other tests as indicated), correction of the hypoglycemia, frequent monitoring of serum glucose, administration of medications including dextrose, glucagon, and occasionally octreotide, patient education, and at discharge adjustment of daily medications if needed.