Abstract: Anne attended Vassar College as an undergrad. In college, Anne played basketball, field hockey and lacrosse. After winter break, she no longer felt like herself, stayed in her room listening to the Rubber Soul album on repeat, and had violent thoughts. One morning, overcome by a panic, Anne ran outside screaming. Her friends raced after her and forced her to go to the little health center on campus. After a while, a psychiatrist asked Anne about the problem. She said nothing, but after a few days, it was clear she would not be let out until she talked. She told the psychiatrist she wanted to kill people. He asked Anne what she wanted to do in life, and she told him she wanted to be a doctor. He said it was a bad idea; she should take some time off from school. Eventually, her depression, which lasted for months, stopped on its own, but it was not the last time she would be depressed. Anne spent summers in Chicago working at local hospitals. Anne got good grades. She was a chemistry major and philosophy and art history minor. Anne’s pediatrician suggested she apply to institutions offering a combined MD/PhD program so she could work in the lab and/or with patients. She graduated summa cum laude in chemistry and thirteenth in the 1969 class of 400.