Cognitive Impairment in Major Depressive Disorder Clinical Relevance, Biological Substrates, and Treatment Opportunities
Book contents
- Cognitive Impairment in Major Depressive DisorderClinical Relevance, Biological Substrates, and Treatment Opportunities
- Cognitive Impairment in Major Depressive Disorder
- Copyright page
- Contents
- Figures
- Tables
- Contributors
- Preface
- Abbreviations
- Part I Clinical relevance of cognitive dysfunction in major depressive disorder
- 1 Does cognitive dysfunction predate the onset of incident depression?
- 2 Understanding the importance of cognitive dysfunction and cognitive change in major depressive disorder
- 3 Cognition in MDD: implications for primary care
- 4 Neurocognition in pediatric depression
- 5 Neuroanatomy of cognition in major depressive disorder
- 6 Hot and cold cognition in major depressive disorder
- 7 Social cognition and emotional processing in major depressive disorder
- 8 The role of social cognition in major depressive disorder
- 9 Are cognitive deficits in major depressive disorder progressive?
- 10 Implications of cognitive impairments on functional outcomes in major depressive disorder
- Part II Underlying biological substrates associated with cognitive dysfunction in major depressive disorder
- Part III Evaluating cognitive dysfunction in major depressive disorder
- Part IV Treatment opportunities for ameliorating cognitive dysfunction in major depressive disorder
- Index
- References
9 - Are cognitive deficits in major depressive disorder progressive?
from Part I - Clinical relevance of cognitive dysfunction in major depressive disorder
Published online by Cambridge University Press: 05 March 2016
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Edited in association with
Book contents
- Cognitive Impairment in Major Depressive DisorderClinical Relevance, Biological Substrates, and Treatment Opportunities
- Cognitive Impairment in Major Depressive Disorder
- Copyright page
- Contents
- Figures
- Tables
- Contributors
- Preface
- Abbreviations
- Part I Clinical relevance of cognitive dysfunction in major depressive disorder
- 1 Does cognitive dysfunction predate the onset of incident depression?
- 2 Understanding the importance of cognitive dysfunction and cognitive change in major depressive disorder
- 3 Cognition in MDD: implications for primary care
- 4 Neurocognition in pediatric depression
- 5 Neuroanatomy of cognition in major depressive disorder
- 6 Hot and cold cognition in major depressive disorder
- 7 Social cognition and emotional processing in major depressive disorder
- 8 The role of social cognition in major depressive disorder
- 9 Are cognitive deficits in major depressive disorder progressive?
- 10 Implications of cognitive impairments on functional outcomes in major depressive disorder
- Part II Underlying biological substrates associated with cognitive dysfunction in major depressive disorder
- Part III Evaluating cognitive dysfunction in major depressive disorder
- Part IV Treatment opportunities for ameliorating cognitive dysfunction in major depressive disorder
- Index
- References
Information
- Type
- Chapter
- Information
- Cognitive Impairment in Major Depressive DisorderClinical Relevance, Biological Substrates, and Treatment Opportunities, pp. 110 - 124Publisher: Cambridge University PressPrint publication year: 2016
References
Airaksinen, E., Wahlin, A., Larsson, M., & Forsell, Y. (2006). Cognitive and social functioning in recovery from depression: Results from a population-based three-year follow-up. Journal of Affective Disorders, 96(1–2): 107–110.CrossRefGoogle ScholarPubMed
Austin, M. P., Mitchell, P., & Goodwin, G. M. (2001). Cognitive deficits in depression: Possible implications for functional neuropathology. British Journal of Psychiatry, 178(3): 200–206.CrossRefGoogle ScholarPubMed
Basso, M. R. & Bornstein, R. A. (1999). Relative memory deficits in recurrent versus first-episode major depression on a word-list learning task. Neuropsychology, 13(4): 557–563.CrossRefGoogle ScholarPubMed
Baune, B. T., Miller, R., McAfoose, J., Johnson, M., Quirk, F., & Mitchell, D. (2010). The role of cognitive impairment in general functioning in major depression. Psychiatry Research, 176(2–3): 183–189.CrossRefGoogle ScholarPubMed
Beats, B. C., Sahakian, B. J., & Levy, R. (1996). Cognitive performance in tests sensitive to frontal lobe dysfunction in the elderly depressed. Psychological Medicine, 26(3): 591–603.CrossRefGoogle ScholarPubMed
Behnken, A., Schöning, S., Gerss, J., Konrad, C., de Jong-Meyer, R., Zwanzger, P., & Arolt, V. (2010). Persistent non-verbal memory impairment in remitted major depression: Caused by encoding deficits? Journal of Affective Disorders, 122(1–2): 144–148.CrossRefGoogle ScholarPubMed
Bhardwaj, A., Wilkinson, P., Srivastava, C., & Sharma, M. (2010). Cognitive deficits in euthymic patients with recurrent depression. Journal of Nervous and Mental Disease, 198(7): 513–515.CrossRefGoogle ScholarPubMed
Biringer, E., Lundervold, A., Stordal, K., Mykletun, A., Egeland, J., Bottlender, R., & Lund, A. (2005). Executive function improvement upon remission of recurrent unipolar depression. European Archives of Psychiatry and Clinical Neuroscience, 255(6): 373–380.CrossRefGoogle ScholarPubMed
Boeker, H., Schulze, J., Richter, A., Nikisch, G., Schuepbach, D., & Grimm, S. (2012). Sustained cognitive impairments after clinical recovery of severe depression. Journal of Nervous and Mental Disease, 200(9): 773–776.CrossRefGoogle ScholarPubMed
Bora, E., Harrison, B. J., Yucel, M., & Pantelis, C. (2013). Cognitive impairment in euthymic major depressive disorder: A meta-analysis. Psychological Medicine, 43(10): 2017–2026.CrossRefGoogle ScholarPubMed
Bremner, J. D., Vythilingam, M., Vermetten, E., Vaccarino, V., & Charney, D. S. (2004). Deficits in hippocampal and anterior cingulate functioning during verbal declarative memory encoding in midlife major depression. American Journal of Psychiatry, 161(4): 637–645.CrossRefGoogle ScholarPubMed
Christensen, M. V., Kyvik, K. O., & Kessing, L. V. (2006). Cognitive function in unaffected twins discordant for affective disorder. Psychological Medicine, 36(8): 1119–1129.CrossRefGoogle ScholarPubMed
Clark, L., Chamberlain, S. R., & Sahakian, B. J. (2009). Neurocognitive mechanisms in depression: Implications for treatment. Annual Review of Neuroscience, 32: 57–74.CrossRefGoogle ScholarPubMed
Colla, M., Kronenberg, G., Deuschle, M., Meichel, K., Hagen, T., Bohrer, M., & Heuser, I. (2007). Hippocampal volume reduction and HPA-system activity in major depression. Journal of Psychiatric Research, 41(7): 553–560.CrossRefGoogle ScholarPubMed
Czeh, B., Simon, M., Schmelting, B., Hiemke, C., & Fuchs, E. (2006). Astroglial plasticity in the hippocampus is affected by chronic psychosocial stress and concomitant fluoxetine treatment. Neuropsychopharmacology, 31: 1616–1626.CrossRefGoogle ScholarPubMed
Davidson, R. J., Pizzagalli, D., Nitschke, J. B., & Putnam, K. (2002). Depression: Perspectives from affective neuroscience. Annual Review of Psychology, 53: 545–574.CrossRefGoogle ScholarPubMed
Den Hartog, H. M., Derix, M. M. A., Van Bemmel, A. L., Kremer, B., & Jolles, J. (1999). Cognitive functioning in young and middle-aged unmedicated out-patients with major depression: Testing the effort and cognitive speed hypotheses. Psychological Medicine, 33(8): 1443–1451.CrossRefGoogle Scholar
Douglas, K. M. & Porter, R. J. (2009). Longitudinal assessment of neuropsychological function in major depression. Australian and New Zealand Journal of Psychiatry, 43(12): 1105–1117.CrossRefGoogle ScholarPubMed
Drevets, W. C. (2000). Neuroimaging studies of mood disorders. Biological Psychiatry, 48(8): 813–829.CrossRefGoogle ScholarPubMed
Duman, R. S. (2002). Pathophysiology of depression: The concept of synaptic plasticity. European Psychiatry, 17(Suppl. 3): 306–310.CrossRefGoogle ScholarPubMed
Frodl, T., Carballedo, A., Fagan, A. J., Lisiecka, D., Ferguson, Y., & Meaney, J. F. (2012). Effects of early-life adversity on white matter diffusivity changes in patients at risk for major depression. Journal of Psychiatry & Neuroscience, 37(1): 37–45.CrossRefGoogle Scholar
Gallagher, P., Robinson, L. J., Gray, J. M., Porter, R. J., & Young, A. H. (2007). Neurocognitive function following remission in major depressive disorder: Potential objective marker of response? Australian and New Zealand Journal of Psychiatry, 41(1): 54–61.CrossRefGoogle ScholarPubMed
Gorwood, P., Corruble, E., Falissard, B., & Goodwin, G. M. (2008). Toxic effects of depression on brain function: Impairment of delayed recall and the cumulative length of depressive disorder in a large sample of depressed outpatients. American Journal of Psychiatry, 165(6): 731–739.CrossRefGoogle Scholar
Gottesman, I. I. & Gould, T. D. (2003). The endophenotype concept in psychiatry: Etymology and strategic intentions. American Journal of Psychiatry, 160(4): 636–645.CrossRefGoogle ScholarPubMed
Grant, M. M., Thase, M. E., & Sweeney, J. A. (2001). Cognitive disturbance in outpatient depressed younger adults: Evidence of modest impairment. Biological Psychiatry, 50(1): 35–43.CrossRefGoogle ScholarPubMed
Hasselbalch, B. J., Knorr, U., Hasselbalch, S. G., Gade, A., & Kessing, L. V. (2013). The cumulative load of depressive illness is associated with cognitive function in the remitted state of unipolar depressive disorder. European Psychiatry, 28(6): 349–355.CrossRefGoogle ScholarPubMed
Herrera-Guzman, I., Gudayol-Ferré, E., Herrera-Abarca, J. E., Herrera-Guzmán, D., Montelongo-Pedraza, P., Padrós Blázquez, F., … Guàrdia-Olmos, J. (2010). Major depressive disorder in recovery and neuropsychological functioning: Effects of selective serotonin reuptake inhibitor and dual inhibitor depression treatments on residual cognitive deficits in patients with major depressive disorder in recovery. Journal of Affective Disorders, 123(1–3): 341–350.CrossRefGoogle ScholarPubMed
Jaeger, J., Berns, S., Uzelac, S., & Davis-Conway, S. (2006). Neurocognitive deficits and disability in major depressive disorder. Psychiatry Research, 145(1): 39–48.CrossRefGoogle ScholarPubMed
Kendler, K. S., Thornton, L. M., & Gardner, C. O. (2000). Stressful life events and previous episodes in the etiology of major depression in women: An evaluation of the “kindling” hypothesis. American Journal of Psychiatry, 157(8): 1243–1251.CrossRefGoogle ScholarPubMed
Kessing, L. V. (2012). Depression and the risk for dementia. Current Opinion in Psychiatry, 25(6): 457–461.CrossRefGoogle ScholarPubMed
Kessing, L. V., Andersen, P. K., Mortensen, P. B., & Bolwig, T. G. (1998). Recurrence in affective disorder. I: Case register study. British Journal of Psychiatry, 172(1): 23–28.CrossRefGoogle ScholarPubMed
Krzysztof, K., Krzystanek, M., Janas-Kozik., M., Klasik, A., & Krupka-Matuszczyk, I. (2015). Impact of pharmacological and psychological treatment methods of depressive and anxiety disorders on cognitive functioning. Journal of Neural Transmission, 122(Suppl. 1): 101–110.Google Scholar
Lampe, I. K., Sitskoorn, M. M., & Heeren, T. J. (2004). Effects of recurrent major depressive disorder on behavior and cognitive function in female depressed patients. Psychiatry Research, 125(2): 73–79.CrossRefGoogle ScholarPubMed
Lee, R. S., Hermens, D. F., Porter, M. A., & Redoblado-Hodge, M. A. (2012). A meta-analysis of cognitive deficits in first-episode major depressive disorder. Journal of Affective Disorders, 140(2): 113–124.CrossRefGoogle ScholarPubMed
Lorenzetti, V., Allen, N. B., Fornito, A., & Yucel, M. (2009). Structural brain abnormalities in major depressive disorder: A selective review of recent MRI studies. Journal of Affective Disorders, 117(1–2): 1–17.CrossRefGoogle ScholarPubMed
MacQueen, G. M., Campbell, S., McEwen, B. S., Macdonald, K., Amano, S., Joffe, R. T., … Young, L. T. (2003). Course of illness, hippocampal function, and hippocampal volume in major depression. Proceedings of the National Academy of Sciences of the United States of America, 100(3): 1387–1392.CrossRefGoogle ScholarPubMed
MacQueen, G. M., Galway, T. M., Hay, J., Young, L. T., & Joffe, R. T. (2002). Recollection memory deficits in patients with major depressive disorder predicted by past depressions but not current mood state or treatment status. Psychological Medicine, 32(2): 251–258.CrossRefGoogle ScholarPubMed
Majer, M., Ising, M., Künzel, H., Binder, E. B., Holsboer, F., & Modell, S. (2004). Impaired divided attention predicts delayed response and risk to relapse in subjects with depressive disorders. Psychological Medicine, 34(8): 1453–1463.CrossRefGoogle ScholarPubMed
Mannie, Z. N., Barnes, J., Bristow, G. C., Harmer, C. J., & Cowen, P. J. (2009). Memory impairment in young women at increased risk of depression: Influence of cortisol and 5-HTT genotype. Psychological Medicine, 39(5): 757–762.CrossRefGoogle Scholar
Marazziti, D., Consoli, G., Picchetti, M., Carlini, M., & Faravelli, L. (2010). Cognitive impairment in major depression. European Journal of Pharmacology, 626(1): 83–86.CrossRefGoogle ScholarPubMed
McIntyre, R. S. (2013). Using measurement strategies to identify and monitor residual symptoms. Journal of Clinical Psychiatry, 74(Suppl. 2): 14–18.CrossRefGoogle ScholarPubMed
McIntyre, R. S., Cha, D. S., Soczynska, J. K., Woldeyohannes, H. O., Gallaugher, L. A., Kudlow, P., … Baskaran, A. (2013). Cognitive deficits and functional outcomes in major depressive disorder: Determinants, substrates, and treatment interventions. Depression and Anxiety, 30(6): 515–527.CrossRefGoogle ScholarPubMed
Monroe, S. M. & Harkness, K. L. (2005). Life stress, the “kindling” hypothesis, and the recurrence of depression: Considerations from a life stress perspective. Psychological Review, 112(2): 417–445.CrossRefGoogle ScholarPubMed
Nagane, A., Baba, H., Nakano, Y., Maeshima, H., Hukatsu, M., Ozawa, A., … Arai, H. (2014). Comparative study of cognitive impairment between medicated and medication-free patients with remitted major depression: Class-specific influence by tricyclic antidepressants and newer antidepressants. Psychiatry Research, 218(1–2): 101–105.CrossRefGoogle ScholarPubMed
Neu, P., Bajbouj, M., Schilling, A., Godemann, F., Berman, R. M., & Schlattmann, P. (2005). Cognitive function over the treatment course of depression in middle-aged patients: Correlation with brain MRI signal hyperintensities. Journal of Psychiatric Research, 39(2): 129–135.CrossRefGoogle ScholarPubMed
Paelecke-Habermann, Y., Pohl, J., & Leplow, B. (2005). Attention and executive functions in remitted major depression patients. Journal of Affective Disorders, 89(1–3): 125–135.CrossRefGoogle ScholarPubMed
Pedersen, A., Küppers, K., Behnken, A., Kroker, K., Schöning, S., Baune, B. T., … Suslow, T. (2009).Implicit and explicit procedural learning in patients recently remitted from severe major depression. Psychiatry Research, 169(1): 1–6.CrossRefGoogle ScholarPubMed
Porter, R. J., Gallagher, P., Thompson, J. M., & Young, A. H. (2003). Neurocognitive impairment in drug-free patients with major depressive disorder. British Journal of Psychiatry, 182: 214–220.CrossRefGoogle ScholarPubMed
Preiss, M., Kucerova, H., Lukavsky, J., Stepankova, H., Sos, P., & Kawaciukova, R. (2009). Cognitive deficits in the euthymic phase of unipolar depression. Psychiatry Research, 169(3): 235–239.CrossRefGoogle ScholarPubMed
Purcell, R., Maruff, P., Kyrios, M., & Pantelis, C. (1997). Neuropsychological function in young patients with unipolar major depression. Psychological Medicine, 27(6): 1277–1285.CrossRefGoogle Scholar
Rapp, M. A., Dahlman, K., Sano, M., Grossman, H. T., Haroutunian, V., & Gorman, J. M. (2005). Neuropsychological differences between late-onset and recurrent geriatric major depression. American Journal of Psychiatry, 162(4): 691–698.CrossRefGoogle ScholarPubMed
Reppermund, S., Ising, M., Lucae, S., & Zihl, J. (2009). Cognitive impairment in unipolar depression is persistent and non-specific: Further evidence for the final common pathway disorder hypothesis. Psychological Medicine, 39(4): 603–614.CrossRefGoogle ScholarPubMed
Rock, P. L., Roiser, J. P., Riedel, W. J., & Blackwell, A. D. (2014). Cognitive impairment in depression: A systematic review and meta-analysis. Psychological Medicine, 44(10): 2029–2040.CrossRefGoogle ScholarPubMed
Sheline, Y. I., Gado, M. H., & Kraemer, H. C. (2003). Untreated depression and hippocampal volume loss. American Journal of Psychiatry, 160(8): 1516–1518.CrossRefGoogle ScholarPubMed
Sheline, Y. I., Sanghavi, M., Mintun, M. A., & Gado, M. H. (1999). Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression. Journal of Neuroscience, 19(12): 5034–5043.CrossRefGoogle Scholar
Trivedi, M. H. & Greer, T. L. (2014). Cognitive dysfunction in unipolar depression: Implications for treatment. Journal of Affective Disorders, 152–154: 19–27.CrossRefGoogle ScholarPubMed
Vythilingam, M., Vermetten, E., Anderson, G. M., Luckenbaugh, D., Anderson, E. R., Snow, J., … Bremner, J. D. (2004). Hippocampal volume, memory, and cortisol status in major depressive disorder: Effects of treatment. Biological Psychiatry, 56(2): 101–112.CrossRefGoogle ScholarPubMed
Weiland-Fiedler, P., Erickson, K., Waldeck, T., Luckenbaugh, D. A., Pike, D., Bonne, O., … Neumeister, A. (2004). Evidence for continuing neuropsychological impairments in depression. Journal of Affective Disorders, 82(2): 253–258.CrossRefGoogle ScholarPubMed
Weingartner, H., Cohen, R. M., Murphy, D. L., Martello, J., & Gerdt, C. (1981). Cognitive processes in depression. Archives of General Psychiatry, 38(1): 42–47.CrossRefGoogle ScholarPubMed
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