This chapter provides a detailed comparative overview of domestic religion in seventeenth- and eighteenth-century London, setting out evidence of a range of domestic devotional activities as performed by households of different faiths, and introducing the legislation which, to varying extents, restricted the open religious expression of these different communities. It considers how larger domestic gatherings involving participants other than members of the household would have been restricted by legislation such as the Conventicle Acts (1664–89), as well as self-regulation within the recently established Jewish communities. This legislation or congregational law drew a distinction between household and family prayer and ‘gathering for worship’ in domestic spaces. The chapter suggests that domestic gatherings for worship were permitted in certain circumstances, and that these circumstances generally coincided with life-cycle events.