Published online by Cambridge University Press: 26 May 2025
Coughing is essential for survival as it clears secretions and foreign bodies from the central airways. Insufficient cough flows and aspiration of saliva are frequent problems in neurological illness and lead to tracheobronchial retention of secretions. Comorbidities like chronic obstructive pulmonary disease, certain medications and failure to adequately humidify the lower airways can lead to hypersecretion, thick and tenacious secretions and ciliary dysfunction, respectively. This can further aggravate any bronchopulmonary retention of secretions, finally leading to atelectasis, pneumonia, respiratory failure as well as death. Noninvasive ventilatory support is effective only if accompanied by adequate management of secretions. This chapter provides a comprehensive overview of the neuronal control, physiology and pathophysiology of coughing and bronchopulmonary retention of secretions as well as effective techniques to reduce secretions and to eliminate them from the airways.
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