In the wake of the COVID-19 pandemic, member states of the World Health Organisation (WHO) agreed to ‘draft and negotiate a WHO convention, agreement or other international instrument on pandemic prevention, preparedness and response’ (Pandemic Treaty).

Proposals for a Pathogen Access and Benefit-Sharing (PABS) System were included from the earliest drafts of the Pandemic Treaty. Access and Benefit-Sharing (ABS) is a transactional mechanism with its origins in international environmental law, where access to genetic resources for use in research and development is provided in exchange for a share of the benefits associated with their use. The purpose is to generate benefits that can be channelled into environmental conservation and sustainable use activities in countries where the genetic resources originate.

The PABS System could be a mechanism for incorporating One Health considerations into the Pandemic Treaty, but this will depend on its design and implementation. This chapter analyses the proposed PABS System in the Pandemic Treaty negotiating texts to determine whether it constitutes a genuine attempt to apply a One Health approach to pathogen ABS.