Indigenous Knowledges, and its evolution across pre- and post-colonial Australia, provide a demonstrated understanding and application of practices beyond One Health. Despite being most impacted by the failures of adopting interdisciplinary One Health approaches, Indigenous Knowledges provide critical methodologies and governance structures to implement and understand the relationship between people, animals, and Country. This chapter explores methods to reconceptualise and reorientate One Health understanding within Australia by aspiring to pre-colonial Indigenous ways of being and doing. Importantly, it also draws upon the post-colonial involvement and learnings of Indigenous peoples in Australia, integrating through self-determination or forced into modern economies and society.