What does it mean to care for culture? How does an individual, a community, a government, a nongovernmental organization, or an international agency care for objects entangled in the legal and illegal antiquities trade, held in contentious museum collections, or at risk due to cultural or natural disasters? How do the various stewards of the past work across the unpredictable boundaries of private, public, and community ownership? Caring for culture involves a range of activities and commitments aimed at safeguarding tangible and intangible cultural representations and ensuring that they remain accessible to present and future generations while honoring the traditions, beliefs, and identities of the contemporary communities. This editorial introduction to this thematic issue of Advances in Archaeological Practice begins with an analysis of the duty of care for the Neo-Assyrian reliefs at the Virginia Theological Seminary, asking whether the decision to sell one of their fragments was caring for culture or a commodification of the past. The remaining contributions to this issue share the theme of caring for culture, acknowledging and building on the enduring scholarship of Neil J. Brodie and Patty Gerstenblith.