Mixed reality simulations such as TeachLivE and Mursion have been increasingly utilised to prepare teachers for inclusive classrooms. The use of mixed reality simulations, which combine elements of both virtual and augmented reality, offers immersive and interactive experiences that can enhance teacher training in various ways. These simulations provide preservice teachers with realistic and safe spaces to practise inclusive communication, pedagogy, and classroom management. Each scenario can be tailored to provide practice in specific skills and support preservice teachers in meeting the Australian Institute for Teaching and School Leadership standards. This is especially helpful in view of today’s inclusive classes, as avatars in the simulations are neurodiverse, representing students of various abilities and personalities. The authors define mixed reality simulations, describe various ways that simulations have been used to support students in special and inclusive education, and describe a case study of simulations used for parent–teacher meetings and for inclusive classroom management in an Australian university. Lastly, they suggest directions for future research and practice.