There are no known written records pertaining to the origins of the enigmatic bronze ‘Lion’ that stands atop one of the two large columns of the Piazzetta in St Mark’s Square, Venice (Italy). Representing the Venetian Winged Lion, a powerful symbol of statehood, the sculpture was installed during a time of political uncertainty in medieval Mediterranean Europe, yet its features do not reflect local artistic conventions. Here, the authors argue that stylistic parallels are found in Tang Dynasty China (AD 618–907); employing lead isotope analysis, they further show that the figure was cast with copper isotopically consistent with ore from the Lower Yangzi River basin.