Chapter 3, “Experiments in Risk: Women and Clinical Trials,” follows feminist advocates as they set out to use the law to mandate the inclusion of women in clinical trials. With the advent of HIV treatment, people with HIV began to survive longer. A new problem emerged: Women were being excluded from clinical trials due to a 1977 Food and Drug Administration (FDA) guideline concerned about the impact of experimental drugs on women’s reproduction and the fetus. Not only did this mean that women could not access experimental treatments, it also resulted in confusion around how to treat women with HIV. Feminists began to advocate for a change in the FDA guidance which was excluding women from clinical trials. In keeping with the broader demands in the feminist movement at the time, feminists asserted that women should be able to choose to enroll in trials despite potential exposure to risks. Buoyed by ideas of choice and bodily autonomy, feminist AIDS activists were able to undo the FDA’s reticence to enroll women in clinical trials altering scientific research in HIV and beyond.

Chapter 1, “‘We Are Not Immune’: A New Branch of the Feminist Women’s Health Movement,” begins by describing the emergence of a new coalition of feminists who turned their attention to the HIV epidemic in an attempt to understand how the virus would impact women. Together they realized that HIV was killing women more often than the those in charge of the AIDS response acknowledged. The failure to recognize and respond to issues facing women with HIV was due, in part, to the Centers for Disease Control and Prevention definition of AIDS that did not include gynecological infections. The incomplete definition of AIDS resulted in a lack of data on women with HIV and impacted the Social Security Administration’s determinations of who should receive benefits. Allying with lawyers and fellow activists, feminists set out to challenge the law and science of the epidemic.

Chapter 2, “Litigating Risk: The Law and Politics of Disease in the Administrative State,” turns to the litigation and activism that resulted in the shift in the Centers for Disease Control and Prevention definition of AIDS and turned attention to women’s risk of contracting HIV. The chapter tracks how litigation and advocacy were central to the shift in the CDC definition of AIDS. Feminist success would result in many more women being diagnosed with HIV, resulting in a greater ability to access benefits. This life-changing shift would mark a major victory for the feminist women’s health movement.

This chapter, by incarcerated writer John J. Lennon, explores the history of prison journalism through the careers of two writers, Wilbert Rideau and Dannie M. Martin. While both became journalists in prison, their writing careers took different forms. Rideau, serving a life sentence for murder in Louisiana, wrote in the typical, detached style of print journalists and helmed one of the most successful prison newspapers of all time, The Angolite, which was nominated for seven National Magazine Awards during his tenure as editor. Martin, serving a thirty-three-year sentence for bank robbery in federal prison, published voice-driven columns and freelanced for the San Francisco Chronicle. Both exposed pressing, overlooked crises behind bars and both risked reprisals from fellow prisoners and the staff responsible for their safety. Their stories of “committing journalism” contain timely lessons for incarcerated writers and prison administrators as the current renaissance of prison journalism continues to grow.

The CIA remained a fixture at the heart of Indian civil debate throughout the 1980s. To the very end of the Cold War, the political fortunes of Indira Gandhi, and her son, and successor, Rajiv Gandhi, were intertwined with a series of espionage scandals in which, almost inevitably, the CIA figured prominently. This chapter examines the Reagan administration’s reliance of the CIA as a cold war foreign policy tool and its difficulties in securing Indian support to counter what officials in Washington perceived to be an alarming and unacceptable expansion in Soviet disinformation activity in the subcontinent. It explores the assassinations of Indira and Rajiv Gandhi and how these two tragic events came to be connected by South Asians with the Agency and its earlier CIA involvement in subversion and political assassination in the Global South. As the Cold War approached its end, and Hindu nationalism, rampant corruption, and political violence gripped India, the chapter considers why national powerbrokers in the subcontinent were once again unable to resist urging citizens to ‘look the other way’ and attribute the country’s troubles to a ubiquitous foreign hand?

During the 1980s, the AIDS crisis unleashed a torrent of animosity against gays and lesbians. As hatred rose, so too did physical assaults. Most of the perpetrators were teenagers, who did not just torment queer adults – they also directed their anger and hatred at their peers. As a result, a substantial percentage of gay and lesbian youth dropped out of school, abused alcohol and drugs, and attempted suicide. Two types of violence consequently plagued queer life: violence from attackers and self-harm. Some advocates responded by focusing on preventing attacks on the streets. They worked with police to improve their responses and lobbied legislators to enact hate crimes protections, which helped make antiqueer violence visible. Others, typically teachers and parents of queer children, focused on creating support systems in schools, so that gay and lesbian teens would not give up hope for a better future.

, During the 1980s and early 1990s, as the HIV/AIDS epidemic swept the country, thousands of gay men and lesbians perished from AIDS-related infections. Their same-sex partners quickly discovered that they had no rights because the law did not recognize their relationships. Advocates consequently pressed municipalities to adopt domestic partnership programs, a concept that originated in union efforts to secure benefits for unmarried partners. In the 1980s, cities, towns, and counties around the country began offering both health benefits to their employees as well as registries where all couples could record their commitment. The total number of these programs were small, and the rights they offered were limited. However, they helped produce new debates over the nature and meaning of family. They also inspired queer workers in the private sector to demand domestic partnership benefits from their employers. By the mid-1990s, domestic partnership benefits had become a mainstay of corporate America.

This chapter details the epidemiology, route of spread, prevalence, incubation period and at-risk groups relating to HIV. It gives information on symptoms, laboratory diagnosis, treatment, prophylaxis and infection control.

As a socially and politically engaged composer, Leonard Bernstein created works for the stage that dramatize and explicate the changing status of women, gender relations, and heteronormative sexuality in the society around him. His Trouble in Tahiti (1951), for all its parodic hilarity, constitutes a powerful critique of bourgeois marriage under McCarthyism and establishes the garden as a recurring trope in his subsequent theatrical compositions. The woman-authored Wonderful Town (1953) turns a nostalgic eye on working women in 1930s Greenwich Village, and, elsewhere in Manhattan, West Side Story (1957) both advances the garden trope and gives us Anita, the wise and powerful Latina. In Trouble in Tahiti’s sequel, A Quiet Place (1983) the garden returns musically and textually to prompt a loving reconciliation between non-binary characters and the family patriarch, brokered by a woman.

Health and science diplomacy is the activity of deploying international cooperation in the service of science and public health, and using global health and science efforts to achieve foreign-policy goals. As a bridge between the scientific community and decision-makers in government, a science or health diplomat must understand the work of both and, ideally, how they think. Scientists see a pattern or anomaly in nature and try to gather data and evidence to explain it. They publish their findings in peer-reviewed scientific journals. But those findings also have to be packaged and communicated to nonscientists, because the data rarely speaks for itself. This is where science diplomats come in. They need to understand the evidence and incorporate it into persuasive arguments that can influence policymakers to elevate the potential threat as a priority and take action.

This chapter features the contributions of influential and lesser-known essayists who have written persuasively and engagingly on gender and sexuality in the twentieth and twenty-first centuries. Issues of identity and difference have had a profound effect on the writing of our age, and certainly on the essay, the most elusive of genres. This chapter considers the intersections of the essay, gender, and queer studies/consciousness over the last few decades, first in a general sense, and then through the lens of specific essayists who have had the most significant impact on the direction of the essay since 1970 in the United States. Beginning with second-wave feminism, this chapter discusses the work of those essayists in feminist and LGBTQ+ communities whose foundational writing on gender still resonates today. The chapter examines important essays that emerged from third- and fourth-wave feminism and then pursues the stylistic and thematic innovations brought by lesbian, gay, trans, and queer writers who have explored topics such as gender as performance, HIV and AIDS, misogyny and misandry, intersectionality, discrimination, and the medicalization and mediatization of desire.

This chapter extends the consideration of the changing global burden of diseases and discusses what is required to mount an effective response to public health challenges, particularly in countries where people are living in extreme poverty. It considers the role of international development assistance and the responsibilities of the international community in improving the health of poor people.

Human immunodeficiency virus (HIV) pathophysiology is driven by the degree to which the patient is immunocompromised reflected by the CD4+ count roughly stratifying into three groups: > 500 cells/µL, 200–500 cells/µL, and < 200 cells/µL.

In the Emergency Department, patients present with diverse infectious diseases. Some diseases require a keen eye from the clinician to diagnose and prevent transmission and progression. HIV and TB are two conditions that are easily overlooked in the ED, yet are the two deadliest infectious diseases in the world. The HIV/AIDS epidemic has been a challenge to the United States health system since the 1980s and continues to represent major health and economic burden. TB cases in the US had been down trending in the 1950s, but since 1985 cases began to rise in urban areas where large communities of immigrants are present. The HIV and TB pandemics are largely intertwined because TB is a major cause of death in HIV patients. Most cases in the US are concentrated in urban areas of low income. Individuals of color, those experiencing homelessness, engaging in high-risk sexual behavior, and those with substance use disorder are the most likely to be affected. Advances in therapeutics as well as the development of screening modalities have made significant progress. The Emergency Department is the major point of contact for diagnosis and linkage to long-term care.

In South Africa in the 1990s Prof. Robert Pattinson asked the minister of health to establish a CEMD based on the UK model. The first Report appeared in 1998. During the AIDS epidemic the president and officials were denialists and tried to alter the Reports. The Enquiry developed a system to report 'great saves'. Politicians were supportive and maternal mortality fell to 97/100,000 in 2019. In India, Dr VP Paily is the coordinator of Kerala’s Confidential Review of Maternal Deaths. The KFOG was founded in 2002 and the Review began in 2003, stimulated by the WHO. The government authorised hospitals to give the KFOG anonymised records of maternal deaths. Quality standards were developed, helped by NICE International. In 2019 the maternal mortality rate was 28/100,000. In the USA Prof. Elliott Main is the medical director of the California Maternal Quality Care Collaborative (CMQCC), established when mortality rose in the 2000s. It produced toolkits to tackle the leading causes and in 2012 established the Maternal Data Center, combining social and hospital data. Severe maternal morbidity is scrutinised. Mortality fell and similar initiatives have spread across the USA.