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Immediate and long-term efficacy of persistent throat symptoms to gastric inlet patch ablation

Published online by Cambridge University Press:  24 July 2025

Chang Woo Lee*
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, University Hospitals Dorset NHS Foundation Trust, Poole, UK
Tabi Unsworth-White
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, University Hospitals Dorset NHS Foundation Trust, Poole, UK
Roanna Norman
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, University Hospitals Dorset NHS Foundation Trust, Poole, UK
Sebastian Matthew Joseph Powell
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, University Hospitals Dorset NHS Foundation Trust, Poole, UK
Natalija Snovak
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, University Hospitals Dorset NHS Foundation Trust, Poole, UK
Kate J Heathcote
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, University Hospitals Dorset NHS Foundation Trust, Poole, UK
Lachlan Ayres
Affiliation:
Department of Gastroenterology, University Hospitals Dorset NHS Foundation Trust, Poole, UK
*
Corresponding author: Chang Woo Lee; Email: changwoo.lee@nhs.net

Abstract

Objective

Efficacy of gastric inlet patch (GIP) ablation using argon plasma coagulation (APC) for patients presenting with persistent throat symptoms was evaluated.

Methods

Retrospective observational study from a single university hospital. Consecutive patients who had GIP ablation for persistent throat symptoms between 01/10/2018-31/10/2023 were reviewed and patients who met all of the set inclusion and exclusion criteria were included in this study for analysis.

Results

50% (n = 18/36) of patients responded to APC ablation (median follow-up 3 months) with their post-ablation GETS score decreasing by 30-100%. Long-term follow-up results could be obtained from 22 patients (n = 22/36) and 75% (n = 9/12) had their clinical effects maintained (median follow-up 4.5 years; range 2.7–5.8 years).

Conclusion

GIP ablation can be a very effective treatment for patients with persistent throat symptoms with its therapeutic effects long-lasting. Future studies should focus on evaluating the optimal patient selection process for GIP ablation for persistent throat symptoms.

Information

Type
Main Article
Copyright
© The Author(s), 2025. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED.

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