This study examines the impact of Colombia’s mental health system reforms (1999–2021) on suicide mortality trends using national vital statistics data (51,924 suicide-related deaths). Through joinpoint regression and interrupted time series analyses, we assessed age-standardized suicide rates (ASSRs) across demographic subgroups. Results revealed no statistically significant associations between policy reforms and suicide trends, despite Colombia’s progressive legislative advancements, including Law 1616 (2013) and expanded mental health services. Key findings include (1) declining ASSR for adolescents (−0.75% annually, p < 0.001) but rising rates among women (+3.8% post-2012, p < 0.05); (2) rural areas consistently exhibited higher ASSRs than urban settings; and (3) reforms showed nonsignificant immediate or sustained effects (p > 0.05). The study underscores the complexity of suicide determinants, suggesting that structural factors (e.g., socioeconomic disparities) may outweigh health-sector interventions. These findings highlight the need for integrated, context-specific suicide prevention strategies in Colombia and similar settings.

In many countries, overall animal experimentation is not significantly decreasing or becoming less severe. Does this show that these countries’ programs to promote alternatives and the “three Rs” of “replace, reduce, refine” are failing? Scholars and activists sometimes take this for granted, but representatives of “three Rs” programs have disagreed. This article makes two contributions to the debate: one conceptual and one normative. First, it draws attention to the distinction between evaluating impact (whether a program makes a difference) and evaluating sufficiency (whether a program makes enough of a difference to achieve its goals). Total numbers are typically unhelpful in assessing impact, but depending on goals, they can be relevant in assessing sufficiency. Second, this article argues that an overall decrease in harm to animals in experimentation is a sensible policy goal. This article concludes with suggestions for how to go beyond the “three Rs” to effect overall change.

The Biden administration requested comments regarding “Public and Private Sector Uses of Biometric Technologies” in the Federal Register from October 2021 to January 2022. This generated 130 responses, helped shape the “Blueprint for an AI Bill of Rights,” and resulted in Executive Order 14110 on “Safe, Secure, and Trustworthy Development and Use of Artificial Intelligence.” While the Trump administration immediately rescinded this executive order, these comments provide insight into salient AI biometrics technologies and relevant political players. We first identify AI biometric technologies before asking which institutions and individuals commented (RQ1), and what the substance and tenor of responses were regarding the opportunities and threats posed by AI biometrics (RQ2-a) based on respondent type (RQ2-b). We use text mining and qualitative analyses to illuminate how uncertainty about AI biometric technology in this nascent policy subsystem reflects participants’ language use and policy preferences.