Efficacy and safety of an alpha 7-nicotinic acetylcholine receptor agonist, VQW-765, in subjects with performance anxiety: randomised, double-blind, placebo-controlled trial: commentary, Baldwin et al
Published online by Cambridge University Press:
19 August 2025
Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, UKHampshire and Isle of Wight Healthcare NHS Foundation Trust, Southampton, UK
Nathan T. M. Huneke
Affiliation:
Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, UKHampshire and Isle of Wight Healthcare NHS Foundation Trust, Southampton, UK
An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)
Article purchase
Temporarily unavailable
References
1
He, Y, Polymeropoulos, C, Mohrman, M, Truslow, S, Xiao, C, Wu, Y, et al.Efficacy and safety of an alpha 7-nicotinic acetylcholine receptor agonist, VQW-765, in subjects with performance anxiety: randomised, double-blind, placebo-controlled trial. Br J Psychiatry2025; 9: 1–8.Google Scholar
2
Lee, CH, Hung, SY.Physiologic functions and therapeutic applications of α7 nicotinic ACh receptor in brain disorder. Pharmaceutics2022; 15: 31.10.3390/pharmaceutics15010031CrossRefGoogle Scholar
3
Feuerbach, D, Pezous, N, Weiss, M, Shakeri-Nejad, K, Lingenhoehl, K, Hoyer, DI, et al.AQW 051, a novel, potent and selective α 7 nicotinic ACh receptor partial agonist: pharmacological characterization and phase I evaluation. Br J Pharmacol2015; 172: 1292–304.10.1111/bph.13001CrossRefGoogle Scholar
4
Hampsey, E, Perkins, A, Young, AH.BNC210: an investigational α7-nicotinic ACh receptor modulator for the treatment of anxiety disorders. Exp Opin Investig Drugs2023; 32: 277–82.10.1080/13543784.2023.2192922CrossRefGoogle ScholarPubMed
5
Labuschagne, I, Grace, C, Rendell, P, Terrett, G, Heinrichs, M.An introductory guide to conducting the Trier Social Stress Test. Neurosci Biobehav Rev2019; 107: 686–95.CrossRefGoogle ScholarPubMed
6
Huneke, NTM, Rowlatt, H, Hyde, J, McEwan, A, Maryan, L, Baldwin, DS, et al.A novel procedure to investigate social anxiety using videoconferencing software: a proof-of-concept study. Psych Res2022; 316: 114770.10.1016/j.psychres.2022.114770CrossRefGoogle ScholarPubMed
7
Saint, SA, Moscovitch, DA.Effects of mask-wearing on social anxiety: an exploratory review. Anxiety Stress Coping2021; 34: 487–502.CrossRefGoogle ScholarPubMed
8
von Majewski, K, Kraus, O, Rhein, C, Lieb, M, Erim, Y, Rohleder, N.Acute stress responses of autonomous nervous system, HPA axis, and inflammatory system in posttraumatic stress disorder. Transl Psychiatry2023; 13: 36.CrossRefGoogle ScholarPubMed
eLetters
No eLetters have been published for this article.