In his interesting account of the history of Brentry Hospital, Dr. Janear described what was done by Harold and Katherine Burden. They came to Bristol in 1895, when Mr. Burden was appointed chaplain to Horfield Prison. They had worked in the East End of London and were much influenced by the achievements of Octavia Hill. Now they turned their attention to the mentally subnormal, and Stoke Park Colony was opened in 1909. Much later, in 1933, this earlier work was furthered by Mr. Burden’s second wife, who established the Burden Mental Research Trust for the study of the causation and inheritance of normal and abnormal mentality. She also supported the foundation of the Burden Neurological Institute in 1939; its illustrious achievements have set a stamp of excellence on our national contribution to the scientific study of mental subnormality. The classical work of Professor Golia, Dr. R. M. Norman, Dr. Fraser Roberts and Dr. Grey Walter, to mention only four of the brilliant workers associated with Stoke Park and the Burden Neurological Institute, has laid solid foundations for the biological study of mental subnormality in this country. Among present workers of this group, Dr. Heaton-Ward and Dr. Janear have added their own remarkable contributions, including their textbooks on mental subnormality which have become classics in their own right.