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Disturbed Endocrine Function in the Psychoses

II: Discriminant Function Analysis of Multihormone Data

Published online by Cambridge University Press:  02 January 2018

L. J. Whalley ,
J. E. Christie ,
D. H. R. Blackwood ,
J. Bennie ,
H. Dick ,
I. M. Blackburn  and
G. Fink
L. J. Whalley*
Affiliation:
Edinburgh University Department of Psychiatry
J. E. Christie
Affiliation:
MRC Brain Metabolism Unit
D. H. R. Blackwood
Affiliation:
Edinburgh University Department of Psychiatry
J. Bennie
Affiliation:
MRC Brain Metabolism Unit
H. Dick
Affiliation:
MRC Brain Metabolism Unit
I. M. Blackburn
Affiliation:
University Department of Psychiatry, The Kennedy Tower, Royal Edinburgh Hospital, Morningside Park, Edinburgh, EH10 5HF
G. Fink
Affiliation:
MRC Brain Metabolism Unit, Department of Pharmacology, 1 George Square, Edinburgh
*
∗ Correspondence
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Abstract

Discriminant function analyses were performed on plasma concentrations of prolactin, growth hormone, Cortisol, TSH, and the neurophysins measured over 17 hours in 70 newly admitted drug-free psychiatric patients and 35 control subjects. The hormone data distinguished between patients with different classes of drug-free psychosis (26 schizophrenic, 12 with manic disorder, 10 with major depressive disorder, psychotic subtype, 9 with schizoaffective mania (SAM)). Higher plasma Cortisol and lower TSH concentrations separated eight of nine SAM patients from all others.

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Type
Papers
Information
The British Journal of Psychiatry , Volume 155 , Issue 4 , October 1989 , pp. 462 - 467
Copyright
Copyright © Royal College of Psychiatrists 1989 

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