Studying the diffuse Galactic synchrotron emission (hereafter, DGSE) at arc-minute angular scale is important to remove the foregrounds for the cosmological 21-cm observations. Statistical measurements of the large-scale DGSE can also be used to constrain the magnetic field and the cosmic ray electron density of our Galaxy’s interstellar medium (ISM). Here, we have used the Murchison Widefield Array (MWA) drift scan observations at 154.2 MHz to measure the angular power spectrum (Cℓ) of the DGSE of a region of the sky from right ascension (RA) 349° to 70.3° at the fixed declination –26.7°. In this RA range, we have chosen 24 pointing centers (PCs), for which we have removed all the bright point sources above ∼ 430 mJy (3σ), and applied the Tapered Gridded Estimator (TGE) on residual data to estimate the Cℓ. We use the angular multipole range 65 ≤ ℓ ≤ 650 to fit the data with a model, , where we interpret the model as the combination of a power law (∝ ℓ–β) nature of the DGSE and a constant part due to the Poisson fluctuations of the residual point sources. We are able to fit the model for six PCs centered at α = 352.5°, 353°, 357°, 4.5°, 4° and 1°. We run the Markov Chain Monte Carlo (MCMC) ensemble sampler to get the best-fit values of the parameters A, β and C for these PCs. We see that the values of A vary in the range 155 to 400 mK2, whereas the β varies in the range 0.9 to 1.7. We find that the value of β is consistent at 2 – σ level with the earlier measurement of the DGSE at similar frequency and angular scales.