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The effect of early cyclophosphamide treatment on the subsequent immunity of chickens to coccidial infections

Published online by Cambridge University Press:  06 April 2009

L. P. Joyner  and
C. C. Norton
L. P. Joyner
Affiliation:
Central Veterinary Laboratory, MAFF, New Haw, Weybridge, Surrey
C. C. Norton
Affiliation:
Central Veterinary Laboratory, MAFF, New Haw, Weybridge, Surrey
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Extract

Chicks were treated with cyclophosphamide during the first 3 days of life in order to effect chemical bursectomy. They subsequently showed a reduced capacity for the production of serum agglutinins to Brucella abortus and immunolysins to sporozoites of Eimeria tenella. They also developed a reduced immunity to E. tenella or E. maxima compared with that produced in normal birds. The evidence provided by these experiments for the role of circulating antibodies in immunity to coccidiosis is discussed.

Information

Type
Research Article
Information
Parasitology , Volume 68 , Issue 3 , June 1974 , pp. 323 - 330
Copyright
Copyright © Cambridge University Press 1974

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References

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