Hostname: page-component-cb9f654ff-pvkqz Total loading time: 0 Render date: 2025-09-01T15:47:49.303Z Has data issue: false hasContentIssue false
  • English
  • Français

Studies on short-term application of drugs to Eimeria tenella in tissue culture

Published online by Cambridge University Press:  06 April 2009

R. G. Wilson
R. G. Wilson
Affiliation:
Imperial Chemical Industries Ltd, Pharmaceuticals Division, Alderley Park, Macclesfield, Cheshire, England
Get access Rights & Permissions [Opens in a new window]

Extract

The anticoccidial action of 6 drugs was studied by treating cell cultures with drug for 24 h after inoculation of the cultures with sporozoites of Eimeria tenella. A monitoring technique was used to confirm that the drug was being removed. Only monensin was shown to be coccidiocidal. Amprolium, lasalocid, methyl benzoquate, nicarbazin and robenidine were coccidiostatic at their minimum effective doses. Misleading coccidiocidal effects were observed when higher concentrations of methyl benzoquate, nicarbazin or robenidene were used.

Information

Type
Research Article
Information
Parasitology , Volume 73 , Issue 3 , December 1976 , pp. 283 - 286
Copyright
Copyright © Cambridge University Press 1976

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Article purchase

Temporarily unavailable

References

Itagaki, K., Tsubokura, M. & Otsuki, K. (1974). Studies on methods for evaluation of anticoccidial drugs in vitro. Japanese Journal of Veterinary Science 36, 195–202.Google Scholar
McDougald, L. R. & Galloway, R. B. (1973). Eimeria tenella: anticoccidial drug activity in cell cultures. Experimental Parasitology 34, 189–96.Google Scholar
Ryley, J. F. (1967). Studies on the mode of action of quinolone and pyridone coccidiostats. Journal of Parasitology 53, 1151–60.Google Scholar
Ryley, J. F. & Wilson, R. G. (1971). Studies on the mode of action of the coccidiostat robenidene. Zeitschrift für Parasitenkunde 37, 85–93.Google Scholar
Ryley, J. F. & Wilson, R. G. (1972). Comparative studies with anticoccidials and three species of chicken coccidia in vivo and in vitro. Journal of Parasitology 58, 664–8.CrossRefGoogle ScholarPubMed
Ryley, J. F. & Wilson, R. G. (1975). Laboratory studies with some recent anticoccidials. Parasitology 70, 203–22.CrossRefGoogle ScholarPubMed
Ryley, J. F., Wilson, R. G. & Betts, M. J. (1974). Anticoccidial activity of an azauracil derivative. Parasitology 68, 69–79.CrossRefGoogle ScholarPubMed