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Emerging perspectives: the interplay of taste perception and oral microbiota composition in dietary preferences and obesity

Published online by Cambridge University Press:  21 October 2024

Deepankumar Shanmugamprema Open the ORCID record for Deepankumar Shanmugamprema [Opens in a new window] ,
Karthi Muthuswamy Open the ORCID record for Karthi Muthuswamy [Opens in a new window]  and
Selvakumar Subramaniam Open the ORCID record for Selvakumar Subramaniam [Opens in a new window]
Deepankumar Shanmugamprema
Affiliation:
Department of Research Analytics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, TN, India
Karthi Muthuswamy
Affiliation:
Men’s Health Research Unit, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA
Selvakumar Subramaniam*
Affiliation:
Molecular Physiology Laboratory, Department of Biochemistry, Bharathiar University, Coimbatore, TN India
*
Corresponding author: Selvakumar Subramaniam; Email: selvs20@yahoo.com
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Abstract

Recent advancements in sensory research have brought to light the intricate relationship between taste perception and the oral microbiota, prompting investigations into their influence on human health, particularly in the context of dietary preferences and obesity. This review aims to update the current understanding of how oral microbiota influence taste perception and dietary choices, elucidating shared metabolic pathways between food processing and oral bacteria. Further, this review outlines the mechanisms underlying taste perception, emphasising the role of taste receptors and taste buds in shaping sensory experiences influenced by genetic and environmental factors. Notably, we explore the bidirectional relationship between oral microbiota and taste sensitivity, highlighting the potential impact of microbial composition on taste perception thresholds and implications for dietary habits and health outcomes, such as obesity and dental caries. However, significant research gaps remain, particularly in the understanding of the molecular mechanisms linking oral microbiota with taste sensitivity, as well as the long-term effects of microbiota-targeted interventions. Future research should focus on longitudinal studies and experimental interventions to explore these connections more deeply, offering insights into potential strategies for promoting healthier dietary behaviours and managing diet-related non-communicable diseases.

Keywords

microbial diversityobesityoral microbiotataste budstaste perceptiontaste receptors

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Type
Review Article
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Nutrition Research Reviews , First View , pp. 1 - 10
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© The Author(s), 2024. Published by Cambridge University Press on behalf of The Nutrition Society

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