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Blood Compatibility of Metal Oxide Layers on Stainless-steel

Published online by Cambridge University Press:  11 February 2011

Kanji Tsuru ,
Shinji Takemoto ,
Tatsuhiro Yamamoto ,
Satoshi Hayakawa ,
Akiyoshi Osaka  and
Seisuke Takashima
Kanji Tsuru
Affiliation:
Biomaterials Laboratory, Faculty of Engineering, Okayama University, Okayama, 700–8530, JAPAN
Shinji Takemoto
Affiliation:
Biomaterials Laboratory, Faculty of Engineering, Okayama University, Okayama, 700–8530, JAPAN
Tatsuhiro Yamamoto
Affiliation:
Biomaterials Laboratory, Faculty of Engineering, Okayama University, Okayama, 700–8530, JAPAN
Satoshi Hayakawa
Affiliation:
Biomaterials Laboratory, Faculty of Engineering, Okayama University, Okayama, 700–8530, JAPAN
Akiyoshi Osaka
Affiliation:
Biomaterials Laboratory, Faculty of Engineering, Okayama University, Okayama, 700–8530, JAPAN
Seisuke Takashima
Affiliation:
Co-Operative Research Center, Okayama University, Tsushima, Okayama, 701–1221, JAPAN
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Abstract

We examined blood compatibility of titanium oxide layer on stainless-steel (SUS316L). The oxide layers with varied thickness were yielded on SUS316L plates by dip-coating of sol-gel solution starting from tetraethyltitanate. The blood compatibility was evaluated in term of platelet adhesion using platelet rich plasma. With increase in the thickness of the oxide layer, the number of adherent platelets decreased rapidly, reached minimum around 150nm. This indicated that the thickness of titanium oxide layer affected platelet adhesion.

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References

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