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The relationship between SIgA and chronic granular pharyngitis

Published online by Cambridge University Press:  29 June 2007

Youzhu Li
Youzhu Li*
Affiliation:
(Lanzhou, PR. China)
*
Dr Youzhu Li, Department of ENT, Box 1189, Mount Sinai Hospital, New York, N.Y. 10029, U.S.A.
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Abstract

A survey of the SIgA content in saliva, serum and pharyngeal mucosa with lymphoid tissue (PMLT) of chronic granular pharyngitis patients was conducted by a double antibody PEG radio-immune method. These data were compared with those from a healthy control group. Result shows that SIgA in patients with chronic granular pharyngitis had dissociation of saliva, serum and PMLY. There was low salivary SIgA level but higher levels in serum and PMLT. These data suggest that the saliva and serum immunoglobulin pools are under separate regulation.

Keywords

Pharyngitischronic granularImmunoglobulin A

Information

Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 107 , Issue 6 , June 1993 , pp. 532 - 534
Copyright
Copyright © JLO (1984) Limited 1993

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References

Andre, C., Andre, F., Fargier, M. C. (1978) Distribution of IgAl and IgA2 plasma cells in various normal human tissues and in the jejunum of plasma IgA-deficient patients. Clinical Experimental Immunology 233: 327–331Google Scholar
Bienenstock, J. (1984) Bronchus associated lymphoid tissue. In Immunology of the lung and upper respiratory tract. McGraw-Hill, New York, pp 96–118.Google Scholar
Chen, R. (1983) Immuno-biochemistry. The People's Publishing House, Beijing, p 52.Google Scholar
Claman, H. N., Merrill, D. A., Hartley, T. F (1967) Salivary immunoglobulins: normal adult values and dissociation between serum and salivary levels. Journal of Allergy 40: 151–155CrossRefGoogle ScholarPubMed
Gu, Y. Y. (1982) The secretory IgA and its immunity functions. Journal of Chinese Otorhinolaryngology 17(3): 191–193.Google Scholar
Ma, W. L., Pen, W., Huang, W. H., Hu, Z. X., Huang, X. Y., Lu, S. Z., Zhun, L. H. (1982) The influence of immunity functions after tonsillectomy in children. Journal of Chinese Otorhinolaryngology 17(3): 141–145.Google Scholar
Pierce, A. E. (1959) Specific antibodies of mucous surfaces. Vet-mary Review and Annotation 5: 17–19Google Scholar
Richtsmeier, W. L., Shikhani, A. H. (1987) The physiology and immunology of the pharyngeal lymphoid tissue. Otolaryngologic Clinics of North America 20 (2): 219–228CrossRefGoogle ScholarPubMed
South, M. A., Cooper, M. D., Wollheim, F. A., Hong, R., Good, R. A. (1966) The IgA system. I. Studies of the transport and immunochemistry of IgA in the saliva. Journal of Experimental Medicine 123: 615–619CrossRefGoogle Scholar
Surjan, L. Jr (1987) Tonsils and lympho-epithelial structures in the pharynx as immuno-barriers. Acta Otolaryngology 103(5–6): 369–372.Google ScholarPubMed
Van der Baan, S., Seldenrijk, C. A., Henzen-Logmans, S. C., Draxhage, H. A. (1988) Serous otitis media and immunological reactions in the middle ear mucosa. Acta Otolaryngology 106: 428–434CrossRefGoogle ScholarPubMed
Waldman, R. H. (1970) Secretory IgA in the human serum. Journal of Immunology 105: 43–49Google Scholar
Yao, X. F., Zhu, X. N., Ma, L. T., Feny, Y. C., Yan, Y. X., Cheng, R. (1989) Determination of SIgA in the saliva. Journal of Chinese Otorhinolaryngology 24(4): 242–245.Google Scholar