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Epidemiologic validation of the National Healthcare Safety Network’s updated Clostridioides difficile test method definition

Published online by Cambridge University Press:  14 July 2025

Nicholas A. Turner Open the ORCID record for Nicholas A. Turner [Opens in a new window] ,
Barry Shelton ,
Becky A. Smith ,
Linda Crane ,
Polly Padgette ,
Linda Roach ,
Brittain Wood ,
Diana Alame  and
Deverick J. Anderson Open the ORCID record for Deverick J. Anderson [Opens in a new window]
Nicholas A. Turner*
Affiliation:
Duke University Medical Center, Division of Infectious Diseases, Durham, NC, USA Duke Center for Antimicrobial Stewardship and Infection Prevention, Durham, NC, USA Duke Infection Control Outreach Network, Durham, NC, USA
Barry Shelton
Affiliation:
Duke Infection Control Outreach Network, Durham, NC, USA
Becky A. Smith
Affiliation:
Duke University Medical Center, Division of Infectious Diseases, Durham, NC, USA Duke Center for Antimicrobial Stewardship and Infection Prevention, Durham, NC, USA Duke Infection Control Outreach Network, Durham, NC, USA
Linda Crane
Affiliation:
Duke Infection Control Outreach Network, Durham, NC, USA
Polly Padgette
Affiliation:
Duke Infection Control Outreach Network, Durham, NC, USA
Linda Roach
Affiliation:
Duke Infection Control Outreach Network, Durham, NC, USA
Brittain Wood
Affiliation:
Duke Infection Control Outreach Network, Durham, NC, USA
Diana Alame
Affiliation:
Duke Clinical Microbiology Laboratory, Durham, NC, USA
Deverick J. Anderson
Affiliation:
Duke University Medical Center, Division of Infectious Diseases, Durham, NC, USA Duke Center for Antimicrobial Stewardship and Infection Prevention, Durham, NC, USA
*
Corresponding author: Nicholas A. Turner; Email: nick.turner@duke.edu.
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Abstract

This longitudinal survey examined the effect of the National Healthcare Safety Network’s (NHSN) recently updated Clostridioides difficile test method definition on reporting of hospital-onset C. difficile. Among six hospitals with ≥ 5 years of data available, the updated NHSN definition was associated with improved concordance between predicted versus reported cases.

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Concise Communication
Information
Infection Control & Hospital Epidemiology , First View , pp. 1 - 4
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Copyright
© The Author(s), 2025. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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References

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