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Service disengagement in first episode psychosis: rates and predictors form 2-year longitudinal research in a real-world care setting

Published online by Cambridge University Press:  26 August 2025

L. Pelizza ,
E. Leuci ,
E. Quattrone ,
M. Menchetti  and
F. Catalano
L. Pelizza
Affiliation:
Università di Bologna, Bologna
E. Leuci
Affiliation:
AUSL di Parma, Parma
E. Quattrone
Affiliation:
AUSL di Parma, Parma
M. Menchetti
Affiliation:
Università di Bologna, Bologna
F. Catalano*
Affiliation:
University of Bologna Italy, Bologna, Italy
*
*Corresponding author.

Abstract

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Introduction

Service disengagement is a major problem for “Early Intervention in Psychosis” (EIP). Understanding predictors of engagement is also crucial to increase effectiveness of mental health treatments, especially in young people with First Episode Psychosis (FEP). No Italian investigation on this topic has been reported in the literature to date. The goal of this research was to assess service disengagement rate and predictors in an Italian sample of FEP subjects treated within an EIP program across a 2-year follow-up period.

Objectives

The goal of this research was to assess service disengagement rate and predictors in an Italian sample of FEP subjects treated within an EIP program across a 2-year follow-up period.

Methods

All patients were young FEP help-seekers, aged 12–35 years, recruited within the “Parma Early Psychosis” (Pr-EP) program. At baseline, they completed the Positive And Negative Syndrome Scale (PANSS) and the Global Assessment of Functioning (GAF) scale. Univariate and multivariate Cox regression analyses were carried out.

Results

489 FEP subjects were enrolled in this study. Across the follow-up, a 26 % prevalence rate of service disengagement was found. Particularly strong predictors of disengagement were living with parents, poor treatment adherence at entry and a low baseline PANSS “Disorganization” factor score.

Conclusions

More than a quarter of our FEP individuals disengaged the Pr-EP program during the first 2 years of intervention. A possible solution to reduce disengagement and to facilitate re-engagement of these young patients might be to offer the option of low-intensity monitoring and support, also via remote technology and telemental health care.

Disclosure of Interest

None Declared

Information

Type
Abstract
Information
European Psychiatry , Volume 68 , Special Issue S1: Abstracts of the 33rd European Congress of Psychiatry , April 2025 , pp. S117
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2025. Published by Cambridge University Press on behalf of European Psychiatric Association
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