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Personal recovery in psychosis: neurobiological basis

Published online by Cambridge University Press:  26 August 2025

J. J. M. Jambrina ,
N. Á. Alvargonzález ,
L. P. Gómez  and
M. A. R. Cortina
J. J. M. Jambrina*
Affiliation:
Psychiatry, Hospital Universitario San Agustín, Avilés, Spain
N. Á. Alvargonzález
Affiliation:
Psychiatry, Hospital Universitario San Agustín, Avilés, Spain
L. P. Gómez
Affiliation:
Psychiatry, Hospital Universitario San Agustín, Avilés, Spain
M. A. R. Cortina
Affiliation:
Psychiatry, Hospital Universitario San Agustín, Avilés, Spain
*
*Corresponding author.

Abstract

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Introduction

Personal recovery in psychosis is one of the fields where research and clinical activities are growing faster. But the concept lacks conceptual clarity and internal consistency. As a result, most of the studies evaluating its efectiveness may be biased. As in any other intervention, great improvement in clinical evolution of the users has been claimed. And so, neurobiological changes should be described.

Objectives

This study finds to develop a systematic review of studies describing changes surrounding the recovery process from a neurobiological level.

Methods

Keywords hev been selected in order to find all studies focussing on personal recovery in psychosis from its neurobiological basis. Qualitative studies of personal recovery will be excluded. Cross-sectional, longitudinal as well as intervention studies will be included.

Results

The systematic review is underway. The study protocol will be registered at PROSPERO database.

Conclusions

Most studies researching about personal recovery have been developed taking “personal recovery” as an outcome marker. But this is not enough. We need to clarify the neurobiological basis underlying this concept.

Disclosure of Interest

None Declared

Information

Type
Abstract
Information
European Psychiatry , Volume 68 , Special Issue S1: Abstracts of the 33rd European Congress of Psychiatry , April 2025 , pp. S1073
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2025. Published by Cambridge University Press on behalf of European Psychiatric Association
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