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A Multilevel Investigation of Conduct Problems in Adolescents: Insights from Neural, Cognitive, and Environmental Perspectives

Published online by Cambridge University Press:  26 August 2025

C. Mou ,
Y. Shi ,
P. Liu  and
Y. Wang
C. Mou*
Affiliation:
School of Psychology, University of Nottingham, Nottingham, United Kingdom
Y. Shi
Affiliation:
Department of Psychology, National University of Singapore, Singapore, Singapore
P. Liu
Affiliation:
State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China
Y. Wang
Affiliation:
State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China
*
*Corresponding author.

Abstract

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Introduction

Conduct problems (CP) in adolescents are associated not only with long-term personality and social development challenges, but also impose significant burdens on families, schools, and communities.

Objectives

While numerous risk factors for CP have been identified in prior research, a comprehensive understanding of the underlying deficit mechanisms remains incomplete.

Methods

Utilizing data from the Adolescent Brain Cognitive Development (ABCD) study (N = 11,875), the largest longitudinal investigation of brain development and child health in the United States, we conducted a systematic analysis of the neural, cognitive, and environmental features linked to CP. The findings were further tested for generalizability across diverse cross-cultural datasets.

Results

Our results propose a novel framework that accounts for cognitive deficits associated with CP, while also highlighting the interactions between biological and environmental factors in the development and potential remission of CP in adolescents.

Conclusions

These insights provide valuable directions for future research and intervention strategies targeting adolescent conduct problems.

Disclosure of Interest

None Declared

Information

Type
Abstract
Information
European Psychiatry , Volume 68 , Special Issue S1: Abstracts of the 33rd European Congress of Psychiatry , April 2025 , pp. S569
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2025. Published by Cambridge University Press on behalf of European Psychiatric Association
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