Active treatment of affective disturbances may improve functional outcomes in patients in the early state of psychosis: Results of the PRONIA study.

Raimo K. R. Salokangas*: Affiliation:
Department of Psychiatry, University of Turku, Turku, Finland
Julian Wenzel: Affiliation:
University of Cologne, Faculty of Medicine and University Hospital of Cologne, Cologne, Germany
Tiina From: Affiliation:
Department of Psychiatry, University of Turku, Turku, Finland
Tuula Ilonen: Affiliation:
Department of Psychiatry, University of Turku, Turku, Finland
Reetta-Liina Armio: Affiliation:
Department of Psychiatry, University of Turku, Turku, Finland
Heikki Laurikainen: Affiliation:
Department of Psychiatry, University of Turku, Turku, Finland
Lauri Tuominen: Affiliation:
Department of Psychiatry, University of Turku, Turku, Finland Royal Ottawa Mental Health Centre, Ottawa, Canada
Maija Walta: Affiliation:
Department of Psychiatry, University of Turku, Turku, Finland
Anne Ruef: Affiliation:
Department of Psychiatry and Psychotherapy, Ludwig-Maximilian University, Munich, Germany
Carolina Bonivento: Affiliation:
Scientific Institute, IRCCS E. Medea, Pasian di Prato, Udine, Italy
Dominic Dwyer: Affiliation:
Department of Psychiatry and Psychotherapy, Ludwig-Maximilian University, Munich, Germany Orygen, Melbourne, Australia
Paolo Brambilla: Affiliation:
Department of Neurosciences and Mental Health, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy Department of Pathophysiology and Mental Health, University of Milan, Milan, Italy
Stephen Wood: Affiliation:
Orygen, Melbourne, Australia Centre for Youth Mental Health, University of Melbourne, Melbourne, Australia Department of Psychiatry, University of Oxford, United Kingdom
Rachel Upthegrove: Affiliation:
Department of Psychiatry, University of Oxford, United Kingdom Institute for Mental Health University of Birmingham, United Kingdom
Stefan Borgwardt: Affiliation:
Translational Psychiatry Unit (TPU), Department of Psychiatry and Psychotherapy, University of Luebeck, Germany
Eva Meisenzal: Affiliation:
Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany
Marlene Rosen: Affiliation:
University of Cologne, Faculty of Medicine and University Hospital of Cologne, Cologne, Germany
Theresa Lichtenstein: Affiliation:
University of Cologne, Faculty of Medicine and University Hospital of Cologne, Cologne, Germany
Stephan Ruhrmann: Affiliation:
University of Cologne, Faculty of Medicine and University Hospital of Cologne, Cologne, Germany
Christos Pantelis: Affiliation:
Melbourne Neuropsychiatry Centre, University of Melbourne & Melbourne Health, Melbourne, Australia
Rebekka Lencer: Affiliation:
Translational Psychiatry Unit (TPU), Department of Psychiatry and Psychotherapy, University of Luebeck, Germany Institute for Translational Psychiatry, University of Muenster, Germany
Alessandro Bertolino: Affiliation:
Department of Translational Biomedicine and Neuroscience - University of Bari Aldo Moro, Bari, Italy
Frauke Schultze-Lutter: Affiliation:
Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany Department of Psychology, Faculty of Psychology, Airlangga University, Surabaya, Indonesia University Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland
Anita Riecher: Affiliation:
Department of Psychiatry (Psychiatric University Hospital, UPK), University of Basel, Switzerland
Joseph Kambeitz: Affiliation:
University of Cologne, Faculty of Medicine and University Hospital of Cologne, Cologne, Germany
Lana Kambeitz-Ilankovic: Affiliation:
University of Cologne, Faculty of Medicine and University Hospital of Cologne, Cologne, Germany Department of Psychiatry and Psychotherapy, Ludwig-Maximilian University, Munich, Germany
Nikolaos Koutsouleris: Affiliation:
Department of Psychiatry and Psychotherapy, Ludwig-Maximilian University, Munich, Germany Max Planck Institute for Psychiatry, Munich, Germany Institute of Psychiatry, Psychology & Neuroscience, Department of Psychosis Studies, King’s College London, London, United Kingdom
Jarmo Hietala: Affiliation:
Department of Psychiatry, University of Turku, Turku, Finland
*: *Corresponding author: Raimo K. R. Salokangas MD, PhD, MSc, PsD; Professor of Psychiatry, Department of Psychiatry, University of Turku, Kiinamyllynkatu 13, 5 C, 20500 Turku, Finland. E-mail: Raimo.K.R.Salokangas@utu.fi

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Abstract

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Keywords

Functional outcomes Psychosis Risk to psychosis Prospective follow-up Affective disturbances

Information

Type: Research Article
Information: European Psychiatry , Accepted manuscript , pp. 1 - 38

DOI: https://doi.org/10.1192/j.eurpsy.2025.10113 [Opens in a new window]
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