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A novel experience with remission of severe, recalcitrant fontan-associated protein-losing enteropathy: a case report

Published online by Cambridge University Press:  30 July 2025

Kaitlin R. Tindel Open the ORCID record for Kaitlin R. Tindel [Opens in a new window] ,
Matthew Lemler  and
Sonali S. Patel
Kaitlin R. Tindel*
Affiliation:
Department of Pharmacy, Dallas Children’s Medical Center, Dallas, TX, USA
Matthew Lemler
Affiliation:
Department of Pediatrics, The University of Texas Southwestern Medical Center, Dallas, TX, USA
Sonali S. Patel
Affiliation:
Department of Pediatrics, The University of Texas Southwestern Medical Center, Dallas, TX, USA
*
Corresponding author: Kaitlin R. Tindel; Email: kaitlin.tindel@childrens.com
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Abstract

Protein-losing enteropathy associated with failing Fontan circulation remains a significant challenge in long-term, single-ventricle circulation management. Evidence is very limited regarding medical therapies associated with a reduction in disease severity and morbidity outside of cardiac transplantation. We report a novel experience with remission of recalcitrant protein-losing enteropathy after treatment of Cryptosporidium gastroenteritis with a combination of antimicrobials including nitazoxanide, paromomycin, and azithromycin.

Keywords

Fontanalbuminprotein-losing enteropathyfailingazithromycincryptosporidium

Information

Type
Case Report
Information
Cardiology in the Young , Volume 35 , Issue 7 , July 2025 , pp. 1504 - 1506
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Copyright
© The Author(s), 2025. Published by Cambridge University Press

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References

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