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Endomyocardial fibrosis and mural thrombus in a 4-year-old girl due to idiopathic hypereosinophilia syndrome described with serial cardiac magnetic resonance imaging

Published online by Cambridge University Press:  16 February 2015

Christiana P. Tai ,
Taylor Chung  and
Kishor Avasarala
Christiana P. Tai*
Affiliation:
Graduate Medical Education, UCSF Benioff Children’s Hospital, Oakland, California, USA
Taylor Chung
Affiliation:
Department of Diagnostic Imaging, UCSF Benioff Children’s Hospital, Oakland, California, USA
Kishor Avasarala
Affiliation:
Department of Pediatric Cardiology, UCSF Benioff Children’s Hospital, Oakland, 94609 California, USA
*
Correspondence to: C. P. Tai, UCSF Benioff Children’s Hospital, 747 52nd Street, Oakland, CA 94609, United States of America. Tel: 510-428-3000; Fax: (510) 601-3979; E-mail: ChTai@mail.cho.org
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Abstract

We present the case of a 4-year-old girl with idiopathic hypereosinophilia syndrome, endomyocardial fibrosis, and mural thrombus. This condition is rarely seen in children outside the tropics. Myocardial biopsy is historically the standard for diagnosis. Reports in adult literature, however, have shown the utility of cardiac MRI as a non-invasive tool for diagnosis, prognosis, and monitoring. To our knowledge, this is the first reported case with serial cardiac MRI in a child.

Keywords

Cardiac magnetic resonance imagingidiopathic hypereosinophilia syndromeendomyocardial fibrosis

Information

Type
Brief Reports
Information
Cardiology in the Young , Volume 26 , Issue 1 , January 2016 , pp. 168 - 171
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Copyright
© Cambridge University Press 2015 

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References

1. Brockington, IF, Olsen, EGJ. Löfflerʼs endocarditis and Davies’ endomyocardial fibrosis. Am Heart J 1973; 85: 308–322.Google Scholar
2. Oh, J, Kim, SH, Youn, JC, Choi, BW, Kang, SM. Endomyocardial fibrosis: evaluation with myocardial contrast echocardiography and magnetic resonance imaging. Can J Cardiol 2012; 28: e11–e12.Google Scholar
3. Kleinfeldt, T, Nienaber, CA, Kische, S, et al. Cardiac manifestation of the hypereosinophilic syndrome: new insights. Clin Res Cardiol 2010; 99: 419–427.CrossRefGoogle ScholarPubMed
4. Tai, PC, Ackerman, SJ, Spry, CJ, Dunnette, S, Olsen, EG, Gleich, GJ. Deposits of eosinophil granule proteins in cardiac tissues of patients with eosinophilic endomyocardial disease. Lancet 1987; 1: 643–647.Google Scholar
5. Caudron, J, Arous, Y, Fares, J, Lefebvre, V, Dacher, JN. Endomyocardial fibrosis in the context of hypereosinophilic syndrome: the contribution of cardiac MRI. Diagn Interv Imaging 2012; 93: 790–792.Google Scholar
6. Cheung, SC, Chan, CW. Insights of prognostication of Davies disease: what could we learn from serial magnetic resonance imaging studies? Int J Cardiol 2010; 142: e32–e34.Google Scholar
7. Pillar, N, Halkin, A, Aviram, G. Hypereosinophilic syndrome with cardiac involvement: early diagnosis by cardiac magnetic resonance imaging. Can J Cardiol 2012; 28: e11–e13.Google Scholar
8. Syed, IS, Martinez, MW, Feng, DL, Glockner, JF. Cardiac magnetic resonance imaging of eosinophilic endomyocardial disease. Int J Cardiol 2008; 126: e50–e52.Google Scholar
9. Debl, K, Djavidani, B, Buchner, S, et al. Time course of eosinophilic myocarditis visualized by CMR. J Cardiovasc Magn Reson 2008; 10: 21.CrossRefGoogle ScholarPubMed
10. Laissy, JP, Hyafil, F, Feldman, LJ, et al.. Differentiating acute myocardial infarction from myocarditis: diagnostic value of early- and delayed-perfusion cardiac MR imaging. Radiology 2005; 237: 75–82.CrossRefGoogle ScholarPubMed