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Application of Ozaki technique in the treatment of aortic valve disease in children: a 15-year retrospective review

Published online by Cambridge University Press:  18 August 2025

Zhangwei Wang Open the ORCID record for Zhangwei Wang [Opens in a new window] ,
Honghao Fu  and
Shoujun Li
Zhangwei Wang
Affiliation:
Department of Cardiovascular Surgery, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for Cardiovascular Diseases, Fuwai Hospital, Beijing, China
Honghao Fu
Affiliation:
Department of Cardiovascular Surgery, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for Cardiovascular Diseases, Fuwai Hospital, Beijing, China
Shoujun Li*
Affiliation:
Department of Cardiovascular Surgery, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for Cardiovascular Diseases, Fuwai Hospital, Beijing, China
*
Corresponding author: Shoujun Li; Email: beijing348@qq.com
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Abstract

With the steady improvement in the efficacy of Ozaki technique in children over the past decade, it is more active and widely used in children with aortic valve disease. Ozaki technique has obvious advantages over traditional prosthetic valve replacement. It preserves the natural motion of the aortic annulus, preserves the coordination of the left ventricle, the sinus of Valsalva and the aorta, naturally dilates the aortic root during systole, restores the physiological laminar flow pattern, and retains the continuous growth potential of the aortic annulus. It has good early and mid-term valve durability, no need for anticoagulation, short learning curve time, easy to promote, suitable for a wide range of people, and significant economic benefits, especially in developing countries with serious shortage of medical resources but a large number of CHD patients. Theoretically, Ozaki techniques can be considered in patients of all ages (adults and children) and in those with acquired and congenital aortic valve disease, including those with previous mechanical, bioprosthetic, or Ross procedures. We currently support the concept of using Ozaki technique as a surgical repair method for children with severe aortic valve disease, but the specific strategy should be made individually according to the patient’s condition. This article reviews the past and present, surgical indications, surgical procedures, advantages, prognosis, and prospects of Ozaki technique in treating aortic valve disease in children.

Keywords

Aortic valve repairOzaki techniqueaortic valve neo-cuspidisationpaediatricaortic valve diseaseprospect

Information

Type
Review
Information
Cardiology in the Young , Volume 35 , Issue 8 , August 2025 , pp. 1540 - 1548
Copyright
© The Author(s), 2025. Published by Cambridge University Press

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Footnotes

Zhangwei Wang and Honghao Fu contributed equally to this work.

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