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Is there a possible role for haemostasis in the development of perigraft reaction complicating the modified Blalock Taussig shunt?

Published online by Cambridge University Press:  19 August 2008

Ulrike Salzer-Muhar ,
Ingrid Pabinger-Fasching  and
Sophie Zacherl-Wightman
Ulrike Salzer-Muhar*
Affiliation:
Department of Pediatric Cardiology, General Hospital Vienna, University of Vienna, Austria
Ingrid Pabinger-Fasching
Affiliation:
Department of Haematology and Haemostaseology, General Hospital Vienna, University of Vienna, Austria
Sophie Zacherl-Wightman
Affiliation:
Department of Pediatric Cardiology, General Hospital Vienna, University of Vienna, Austria
*
Ulrike Salzer-Muhar MD, Abteilung für Pediatrische Kardiologie, Univ.-Kinderklinik Wien, Waehringer Guertel 18–20, A–1090 Vienna, Austria. Tel. +43 140 400/3217; Fax +43 140 400/3417; E-mail: ulrike.salzer@akh-wien.ac.at
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Abstract

The perigraft reaction is an unusual complication found in patients in whom a modified Blalock Taussig shunt has been created using a polytetrafluoroethylene graft. We found that, in two infants, consistent laboratory findings during such a perigraft reaction were hypofibrinogenemia, increased levels of thrombin-antithrombin III complex, prothrombinfragment 1 and 2 and products of degradation of fibrin. Normalization of the levels of fibrinogen produced resolution of the perigraft reaction.

Keywords

Modified Blalock Taussig shuntperigraft reactionhealing process of the prosthesisabnormal haemostasis

Information

Type
Brief Reports
Information
Cardiology in the Young , Volume 10 , Issue 3 , May 2000 , pp. 261 - 264
Copyright
Copyright © Cambridge University Press 2000

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References

1.LeBlanc, J, Albus, R, Williams, WG et al. , Serous fluid leakage. A complication following the modified Blalock Taussig shunt. J Thorac Cardiovasc Surg 1984; 88: 310–311.CrossRefGoogle ScholarPubMed
2.Bolton, WCannon, JA. Seroma formation associated with PTFE vascular grafts used as arteriovenous fistulae. Dial Transplant 1981; 10: 60–63.Google Scholar
3.Feil, E, Arnold, G, Borowski, A, Mennicken, U. Perigraft Reaktion. Eine Komplikation nach Anlage eines Prothesenshunts bei Kindern mit angeborenen zyanorischen Herzfehlern. Z Kardiol 1992; 81: 283–289.Google Scholar
4.Al Jubair, KA, Al Fagih, MR, Al Jarallah, AS et al. , Results of 546 Blalock Taussig shunts performed in 478 patients. Cardiol Young 1998; 8: 486–490.CrossRefGoogle ScholarPubMed
5.Board, PG, Loswsky, MS, Miloszweski, JA. Factor XIII: Inherited and acquired deficiency. Blood Reviews 1993; 7: 229–242.CrossRefGoogle ScholarPubMed
6.Ahn, SS, Machleder, HI, Gupta, R, Moore, WS. Perigraft seroma:Clinical, histological and serologic correlates. Am J Surg 1987; 154: 173–178.CrossRefGoogle ScholarPubMed
7.Blumenberg, RM, Gelfand, ML, Dale, AW. Perigraft seroma complicating arterial grafts. Surgery 1985; 97: 194–203.Google ScholarPubMed
8.Ries, M, Singer, H, Hofbeck, M, Klinge, J, Wild, F, Vogel, P. Systemic and local thrombolytic therapy with rt-PA ( Actilyse) in children with congenital heart disease. Monatsschr Kinderheilkd 1994; 142: 205–208.Google Scholar
9.Berger, RMF, Bol-Raap, G, Hop, WJC, Bogers, AJJC, Hess, J. Heparin a s a risk factor for perigraft seroma complicating the modified Blalock Taussig shunt. J Thorac Cardiovasc Surg 1998; 116: 286–293.CrossRefGoogle Scholar