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Published online by Cambridge University Press: 10 July 2025
Background: Hybrid Nerve Sheath Tumours (HNST) were introduced in the WHO Blue Book in the 2016 edition. Since that time, extracranial HNST are commonly identified but intracranial lesions are rare. Methods: A systematic review of the literature was completed. Additionally, chart reviews were completed on two cases of HNST identified at our academic center. Results: 3 reports of intracranial HNST located on a cranial nerve have been published to date. 2 cases of cranial nerve associated HNST have been identified at our academic centre. Conclusions: HNSTs may be underreported in the cranial region.