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Aqueduct Gliosis Caused by Keratin and Cholesterol In a Case of Craniopharyngioma

Published online by Cambridge University Press:  18 September 2015

Dikran S. Horoupian ,
Henryk M. Wisniewski ,
Robert Gamble  and
Arie L. Liebeskind
Dikran S. Horoupian*
Affiliation:
Departments of Pathology (Neuropathology), Neurological Surgery, Neuroradiology and the Rose F. Kennedy Center for Mental Retardation and Human Development, Albert Einstein College of Medicine, The Bronx, New York, U.S.A.
Henryk M. Wisniewski
Affiliation:
Departments of Pathology (Neuropathology), Neurological Surgery, Neuroradiology and the Rose F. Kennedy Center for Mental Retardation and Human Development, Albert Einstein College of Medicine, The Bronx, New York, U.S.A.
Robert Gamble
Affiliation:
Departments of Pathology (Neuropathology), Neurological Surgery, Neuroradiology and the Rose F. Kennedy Center for Mental Retardation and Human Development, Albert Einstein College of Medicine, The Bronx, New York, U.S.A.
Arie L. Liebeskind
Affiliation:
Departments of Pathology (Neuropathology), Neurological Surgery, Neuroradiology and the Rose F. Kennedy Center for Mental Retardation and Human Development, Albert Einstein College of Medicine, The Bronx, New York, U.S.A.
*
Dept. of Pathology, Health Science Center, 700 William Ave., Winnipeg, Canada R3E 0Z3.
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Summary

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Keratin and cholesterol particles released by a craniopharyngioma were shown to be the agents involved in the production of a foreign-body granulomatous arachnoiditis and ependymitis. Some of the particles were seen embedded in the reactive subepen-dymal glial tissue along the aqueduct of Sylvius. It was thought they were a major factor leading to the aqueduc-tal stenosis. However, we have also considered that the change in cerebro-spinal fluid hydrodynamics following the ventriculopleural shunt contributed to the occlusion of the aqueduct.

Information

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 1 , Issue 3 , August 1974 , pp. 184 - 188
Copyright
Copyright © Canadian Neurological Sciences Federation 1974

References

Bagley, C. Jr. (1929). Functional and organic alterations following the introduction of blood into the cerebrospinal fluid. The Intracranial Pressure in Health and Disease. An Investigation of The Most Recent Advances. Research Publications of the Association for research in nervous and mental disease, 8, 217–25.Google Scholar
Bartlett, J. F. (1971). Craniopharyn-gioma — A Summary of 85 Cases. Journal of Neurology, Neurosurgery and Phy-chiatry, 34, 37–41.Google Scholar
Foltz, E. L.; and Shurtleff, D. B. (1966). Conversion of communicating hydrocephalus to stenosis or occlusion of the aqueduc’ during ventricular shunt. Journal of Neurosurgery, 24, 520–9.CrossRefGoogle ScholarPubMed
Gaupp, R. (1942). Ein teratom im seitenventrikel. Nervenarzt, 15, 363–73.Google Scholar
Grover, W. D.; and Balian-Rorke, L. (1968). Invasive cranio-pharyngioma. Journal of Neurology, Neurosurgery and Psychiatry, 31, 580–2.CrossRefGoogle Scholar
Iyer, C. G. S. (1952). Case report of an adamantinoma present at birth. Journal of Neurosurgery, 9, 221–8.CrossRefGoogle Scholar
Kramer, S.; Southard, M.; and Mansfield, C. M. (1968). Radiotherapy in the management of craniopharyngiomas. Further experiences and late results. American Journal of Roentgenology, 103, 44–52.CrossRefGoogle ScholarPubMed
Love, J. G.; and Marshall, T. M. (1950). Craniopharyngiomas (pituitary ada-mantioma). Surgery, Gynecology and Obstetrics, 90, 591–601.Google Scholar
Matson, D. D.; and Crigler, J. F. Jr. (1969). Management of cranio-pharyngioma in childhood. Journal of Neurosurgery, 30, 377–90.CrossRefGoogle Scholar
Olivecrona, H.; and Tonnis, W. (1967). Klinik und behandlung der raumbeengenden intrakraniellen prozesse. Handbuch der Neurochirurgie, IV/4. Springer-Verlag, Berlin, pp. 272.Google Scholar
Ross Russell, R. W.; and Penny-Backer, J. B. (1961). Craniopharyngioma in the elderly. Journal of Neurology Neurosurgery and Psychiatry, 24, 555–64.Google Scholar
Russell, D. S.; and Rubinstein, L. J. (1971). Pathology of Tumors of the Nervous System.Third Edition. Williams and Wilkins Company, Baltimore, pp. 19.Google Scholar
Scarff, J. E. (1941). A new method for treatment of cystic craniopharyngioma by intra-ventricular drainage. Archives of Neurology and Psychiatry, 46, 843–67.CrossRefGoogle Scholar
Zülch, K. J. (1965). Brain Tumors, Their Biology and Pathology. [Translated by Rothballer, A. B.]. Second Edition. Springer Publishing Company, Inc.; New York, pp. 244.Google Scholar