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The Considerations for the Prescription of Valproate as Treatment in Mayo Mental Health Service

Published online by Cambridge University Press:  20 June 2025

Irene Akashie
Affiliation:
Mayo Mental Health Services, Castlebar, Ireland
Rachael Ayodele
Affiliation:
Mayo Mental Health Services, Castlebar, Ireland
Philippa Renton
Affiliation:
Mayo Mental Health Services, Castlebar, Ireland
Sharon Coen
Affiliation:
Mayo Mental Health Services, Castlebar, Ireland
Catherine Kelly
Affiliation:
Mayo Mental Health Services, Castlebar, Ireland
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Abstract

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Aims: To examine current monitoring practices for valproate users within Mayo Mental Health Services and analyse the conditions for which it is prescribed.

Methods: Information on sodium valproate users was collected from clinical records using a data collection tool specifically developed to capture indicative parameters.

Results: Data was collected from 6 community clinics and 4 inpatient units with a total of 69 patients on sodium valproate treatment within the service. Licensed indication was accounted for in 24.6% of patients with 63.8% prescribed valproate for unlicensed use and 11.6% for unknown indication. Amongst the prescribed users 33.3% were male and 66.7% were female with 27.5% of participants being under 55 years old and 72.5% over 55 years old. Out of 39 females using valproate 20.5% were on effective contraceptives and 79.5% were not using any. Regarding the annual physical health check, all participants in the approved inpatient units were compliant as it was part of the inpatient care requirement. 54.5% of patients in the community clinic on valproate had annual physical health reviews and 45.5% were not compliant.

Conclusion: Our examination of Mayo Mental Health Service shows that most valproate use was for unlicensed indications with the majority of the users being female, most of whom were over 55 years of age. This reflects the high percentage of non-effective contraceptive users. There is also inadequate physical health monitoring for patients in the community.

Information

Type
Research
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2025. Published by Cambridge University Press on behalf of Royal College of Psychiatrists

Footnotes

Abstracts were reviewed by the RCPsych Academic Faculty rather than by the standard BJPsych Open peer review process and should not be quoted as peer-reviewed by BJPsych Open in any subsequent publication.

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