from Section 4 - Novel Approaches in Brain Imaging
Published online by Cambridge University Press: 12 January 2021
In 1977, Frans F Jöbsis pioneered a noninvasive method for measuring the hemodynamic oxygenation of biological tissue using near-infrared light (1). This method fostered a new era of near-infrared spectroscopy (NRIS) studies in the field of neuroscience. Over the last two decades, functional NIRS (fNIRS) has been applied to evaluate brain activation in humans in vivo and functional abnormalities in patients with psychiatric illnesses. Along with other functional neuroimaging modalities, such as functional MRI (fMRI), single-photon emission computed tomography (SPECT), and positron emission tomography (PET), studies using fNIRS to investigate mood disorders have been accumulating given the increasingly widespread use of NIRS in the study of psychiatric disorders.
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